pISSN: 1735-8949
eISSN: 1735-9392
Editor–in–Chief:
Fatemeh Davari Tanha, MD.
Vol 6, No 3 (September 2012)
Objective: To investigate the effect of fluoxetine as an SSRI on menstrual disorders.
Materials and methods: In this cross-sectional study 200 women referring to the Islamic Azad University affiliated hospitals during March 2011- March 2010 were divided into 4 groups. All included patients in this study had the chief complaint of mood disorders in peri- menstrual period. All patients received daily vitamin B6 tablets as primitive treatment. In groups A, B and C patients also received daily doses of 10 mg, 20 mg and 40 mg of fluoxetine respectively for 6 months and in group D as the control group fluoxetine was not given. Data were analyzed by spss18 statistical software. Significant difference was set at p<0.05.
Results: In the groups receiving fluoxetine (groups A - C) 34 patients and in control group 5 patients showed irregular menstruation started during fluoxetine administration and following 3 months. Significant difference with p<0.05 was found regarding the incidence of menstrual irregularity between groups with and without fluoxetine prescription.
Conclusion: Fluoxetine consumption leads to increased incidence of menstrual irregularity compared to the control group. The incidence increases with increasing dosage of the drug.
Objective: In this study efficacy of sub lingual Misoprostol was examined in comparison to Oxytocin (I.V.) for inducing of labor in term pregnancy.
Materials and methods: Seventy patients were allocated by blocked randomization to Groups A (n=35, sub lingual Misoprostol 25 μg four hourly to maximum of 5 doses) and B (n=35, continuous Oxytocin infusion).
Results: Delivery active phase and total labor phase were shorter with sublingual Misoprostol in comparison to intravenous Oxytocin (p< 0.001) and the rate of cesarean section was lower in Misoprostol group (p<0.04) but delivery latent phase, meconium staining, uterine hypertonisity and apgar score (1&5 minute) were similar in two groups.
Conclusion: sublingual Misoprostol is better than intravenous Oxytocin for induction of labor at term.
Objective: To determine the pattern of breastfeeding in infants who conceived by assisted reproductive techniques (ART).
Materials and methods: In a cross-sectional study, 312 infants were selected by the non-random consecutive method from ART infants who referred by Royan institute to Child Health Research Department. Infants were born between Septembers 2007and September 2009 in Tehran. Infant nutrition, mother age, ART techniques, birth growth indexes, beginning time and the kind of nutrition and growth pattern until 6 months were considered.
Results: Breastfed infants were 110(35.2%), 46(14.7%) ones were formula fed and 156(50%) were both. The rate of breastfeeding on the first day after birth in neonates with the low birth weight were less than normal birth weight ones .Approximately 36.8% of infants who had normal increase of weight and height till 6 months, began feeding on the first day of life. Mothers' age and ART technique did not affect the beginning time and kind of infants feeding.
Conclusion: The most important factor which affects ART infants' nutrition pattern is their birth weight. The beginning time of feeding affects their weight and length increase till 6 months. Based on reproductive techniques, breastfeeding was similar in different methods of ART.
Objective: Pre-natal diagnosis is the most effected way to prevent genetic diseases in a society. The aim of this research was to show the prevention level of the birth of the children with major thalassemia disorder and the demographic condition of the people referring to the Shahid Dastgheib Genetic Center in Shiraz for the pre natal diagnosis.
Materials and methods: The present research was a cross- sectional (descriptive, analytical) one. In this study, the amount of sampling was done by census in a way that all the case (372 cases) related to the year 2010. The questionnaire was prepared based on the information present in the files. In order to compare the quantitative and qualitative variables, two sample t - test and K sample t- test were used.
Results: Out of 372 fetuses tested, 25.5% had major thalassemia, 48.7% minor thalassemia, 0.8% intermediate, 1.3% sickle cell, and 23.7% were healthy. All the cases diagnosed with thalassemia were introduced for abortion, and abortion was carried out. Major thalassemia was more prevalent in Lore tribes (32.9%), which was more in comparison to the members of others tribes.
Conclusion: In order to prevent major thalassemia, it is important to identify the gene carriers and prevent their marriage. Nevertheless, in many places in the country, especially in the villages and rural areas, the couples do the experiment after they have already gotten emotionally involved and made the arrangements to get married; therefore they're unwilling to stop the marriage. As a result, post-nuptial CVS during pregnancy is crucial.
Objective: To ascertain the unmet needs of family planning & identify the practice of family planning among the urban to rural migrated slum dwellers.
Materials and methods: A cross-sectional descriptive study was done randomly among selected 600 slum dwellers residing in two selected slums of Dhaka city. Data collected by face to face interview using pretested semi structured questionnaire.
Results: Among the respondents 87.7% of were females, illiterate was 60% and most (79.9%) of the houses were katcha and (37.3%) of the families had 5-7 persons in each family. Most families (70%) had monthly income of less than 5000 (app.US$70) taka per month. Majority (89.3%) of the families lived in the villages before coming to Dhaka. About 31.34% were living in present slum for 5-10 years and 80% came for search for better work. It was also found that 33.7% of the couples were not using any contraceptive method. About 29% of these couples did not mention any specific cause for not using family planning method. Only 3.5% of the respondents said of any sort of difficulty in collecting contraceptives and the main difficulty was shyness. As regards knowledge of above consequence of not using contraceptive method 97.7% opined that it would cause unplanned pregnancy, which indicated their awareness towards family planning.
Conclusion: The study found that the respondents were aware about the needs of family planning but a great number of them were not using any contraceptive method without any specific reason. Some behavior change communication activities can be run within these areas to bring them under the family planning methods which eventually enhance the population control activity of the country.
Objective: To determine the effect of paternal age on preterm births in Iranian neonates.
Materials and methods: From January 2005 to January 2006, two hundred eighty one preterm neonates born in Mirza Kuchakkhan Hospital enrolled in this cross-sectional study. A structured questionnaire was applied for recording following data: birth weight, sex, gestational age, maternal age and paternal age. The study was limited to neonates whose maternal age was between 20 and 30 years to eliminate its confounding effect.
Results: Near 50% of fathers were between 30-39 years old and more than half of neonates had gestational age between 35-37 weeks. There were no relation between either paternal age (p= 0.1) or birth weight (p=0.5) and neonatal gestational age. In women with parity one, there was not significant difference between gestational age among different paternal age levels ( p= 0.6) as well as women with parity two and three (p=0.2, p=0.3).
Conclusion: Paternal age has no effect on gestational age and birth.
Objective: To study the qualification of divorce main factors so that it would be clarified proper consultation-intervention solutions to decrease it by counseling methods in the courts and counseling clinics. The divorce is categorized as the most tragic of social phenomenon, the damages and problems of which undergone by the couple and their families before and after divorce and the effective factors of this phenomenon incidence have been studied for many years. Divorce has different factors and it can never clarify a specific one as the main factor of divorce.
Materials and methods: This survey studied the divorce creating factors in divorce applicants in Tehran Family courts (Shahid Mahalati-Vanak) during 2010-2011. The applicants of sampling group were including 300 referred ones from the courts, and the research method was descriptive and cross-sectional accomplishing by structured interview. Findings were shown as frequency and percent.
Results: The results showed that the important factors of divorce request are including in order of psychic factors (93.3%), social and cultural factors (87.3%), sexual factors (88%), economical factors (80.3%), and violence (84.3%), and it may be multi-factors as well.
Conclusion: In addition to recommendation for more study in these fields, the results of this survey suggest to apply the necessary programming in teaching and counseling before the marriage as well as the necessity of informing the couple in receiving professional consults in time of problem incidence and proceeding for divorce in order to prevent from divorce incidence.
A 25-year-old female presented to the infertility OPD with complaints of secondary infertility and pain lower abdomen with watery discharge for the past five days. She had history of undergoing hysterosalpingography in a private hospital ten days back. The interventions included drainage of pyometra, endometrial biopsy for routine and AFB smear/ culture, confirmation of diagnosis by mRNA-based RT-PCR for detection of M. tuberculosis-specific 85B antigen gene, anti-tubercular therapy. Pyometra and tubo-ovarian masses disappeared and patient resumed her normal period post-treatment. Genital tuberculosis was confirmed by mRNA-based RT-PCR and the disease resolved after anti-tubercular therapy. We conclude that a combination of high degree of clinical suspicion and ‘high-precision' gene detection methods (e.g. mRNA) in culture-negative cases may be useful in diagnosis of genital tuberculosis, particularly in infertile patients presenting with pyometra post-hysterosalpingography.
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