Original Articles

The Effect of Paternal Age on Preterm Births; a Survey of 281 Cases

Abstract

Objective: To determine the effect of paternal age on preterm births in Iranian neonates.
Materials and methods: From January 2005 to January 2006, two hundred eighty one preterm neonates born in Mirza Kuchakkhan Hospital enrolled in this cross-sectional study. A structured questionnaire was applied for recording following data: birth weight, sex, gestational age, maternal age and paternal age. The study was limited to neonates whose maternal age was between 20 and 30 years to eliminate its confounding effect.
Results: Near 50% of fathers were between 30-39 years old and more than half of neonates had gestational age between 35-37 weeks. There were no relation between either paternal age (p= 0.1) or birth weight (p=0.5) and neonatal gestational age. In women with parity one, there was not significant difference between gestational age among different paternal age levels ( p= 0.6) as well as women with parity two and three (p=0.2, p=0.3).

Conclusion: Paternal age has no effect on gestational age and birth.

Martin JA, Hamilton BE, Sutton PD, Ventura SJ, Menacker F, Munson ML. Births: final data for 2003.Natl Vital Stat Rep 2005; 54:1-116.

Hovi P, Andersson S, Eriksson JG, Järvenpää AL,Strang-Karlsson S, Mäkitie O et al. Glucose Regulation in Young Adults with Very Low Birthweight. N Engl J Med 2007;356:2053-63.

Aboulghar MA. Perinatal Complications of Assisted Reproduction. Croat Med J 2005; 46:751-8.

Basso O, Olsen J, Christensen K. Low birth weight and prematurity in relation to paternal factors: a study of recurrence. Int J Epidemiol 1999; 28: 695-700.

Klebanoff MA, Mednick BR, Schulsinger C, Secher NJ, Shiono PH. Father's effect on infant birth weight.Am J Obstet Gynecol 1998; 178:1022-6.

Li DK. Changing paternity and the risk of preterm delivery in the subsequent pregnancy. Epidemiology 1999; 10: 148-52.

Yang Q, Wen SW, Leader A, Chen XK, Lipson J, Walker M. Paternal age and birth defects: how strong is the association? Hum Reprod 2006;22;696–701.

Andersen AN, Hansen KD, Andersen PK, Smith GD. Advanced paternal age and risk of fetal death: a cohort study. Am J Epidemiol 2004; 160: 1214–22.

De la Rochebrochard E, Thonneau P. Paternal age and maternal age are risk factors for miscarriage; results of a mulitcentre European study. Hum Reprod 2002; 17: 1649–56.

Slama R, Bouyer J, Windham G, Fenster L, Werwatz A, Swan SH. Influence of paternal age on the risk of spontaneous abortion. Am J Epidemiol 2005; 161: 816–23.

Harlap S, Paltiel O, Deutsch L, Knaanie A, Masalha S, Tiram E, Caplan LS, Malaspina D, Friedlander Y. Paternal age and preeclampsia. Epidemiology 2002; 13: 660–7.

Dockerty JD, Draper G, Vincent T, Rowan SD, Bunel KJ. Case-control study of paternal age, parity and socioeconomic level in relation to childhood cancers. Int J Epidemiol 2001;30:1428–37.

Jayasekara R, Street J. Paternal age and parity in dyslexic boys. J Biosoc Sci 1978; 10:255–61.

Malaspina D, Harlap S, Fenning S. Advancing paternal age and the risk of schizophrenia. Arch Gen Psychiatry 2001;58:361–7.

Miozzo M, Simoni G. The role of imprinted genes in fetal growth. Biol Neonate 2002;81:217–28.

Schwartz D, Mayaux MJ, Spira A, Moscato ML, Jouannet P, Czyglik F, David G. Semen characteristics as a function of age in 833 fertile men. Fertil Steril 1983; 39: 530–5.

Tough SC, Faber AJ, Svenson LW, Johnston DW. Is paternal age associated with an increased risk of low birthweight, preterm delivery, and multiple birth? Can J Public Health 2003;94: 88-92.

Basso O, Wilcox AJ. Paternal Age and Delivery Before 32 Weeks. Epidemiology 2006;17: 475-8.

19. Astolfi P, Pasquale AD, Zonta LA. Paternal age and preterm birth in Italy, 1990 to 1998. Epidemiology 2006;17:218–21.

Chen XK, Wen SW, Krewski D, Fleming N, Yang Q, Walker MC. Paternal age and adverse birth outcomes: teenager or 40+, who is at risk? Hum Reprod 2008;23:1290-6.

Abel EL, Kruger M, Burd L. Effects of maternal and paternal age on Caucasian and native American preterm births and birth weight. Am J Perinatol 2002;19:49–54.

Olshan AF, Ananth CV, Savitz DA. Intrauterine growth retardation as an endpoint in mutation epidemiology: an evaluation based on paternal age. Mutat Res 1995;344:89–94.

Zhu JL, Madsen KM, Vestergaard M, Basso O, Olsen J. Paternal age and preterm birth. Epidemiology 2005;16:259–62.

Bernstein PS, Divon MY. Etiologies of fetal growth restriction. Clin Obstet Gynecol 1997;40:723-9.

Basso O, Olsen J, Christensen K. Low birthweight and prematurity in relation to paternal factors: a study of recurrence. Int J Epidemiol 1999 28:695-700.

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SectionOriginal Articles
Keywords
paternal age gestational birth preterm birth Iran

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How to Cite
1.
Kaveh M, Ghajarzadeh M, Davari Tanha F, Savaheli S, Rezayof E. The Effect of Paternal Age on Preterm Births; a Survey of 281 Cases. J Family Reprod Health. 2012;6(3):125-128.