Tehran University of Medical Sciences Journal of Family and Reproductive Health 1735-8949 6 3 2012 09 14 99 103 Leila Habibi Mirza Khoochakkhan hospital; Tehran University of Medical Sciences, Tehran, Iran. Shirin Niroomanesh Mirza Khoochakkhan hospital; Tehran University of Medical Sciences, Tehran, Iran. Laleh Ghadirian Preventive and Community medicine specialist, Centre for Academic and Heath policy, Tehran Universit 2015 10 04 Objective: In this study efficacy of sub lingual Misoprostol was examined in comparison to Oxytocin (I.V.) for inducing of labor in term pregnancy. Materials and methods: Seventy patients were allocated by blocked randomization to Groups A (n=35, sub lingual Misoprostol 25 μg four hourly to maximum of 5 doses) and B (n=35, continuous Oxytocin infusion). Results: Delivery active phase and total labor phase were shorter with sublingual Misoprostol in comparison to intravenous Oxytocin (p< 0.001) and the rate of cesarean section was lower in Misoprostol group (p<0.04) but delivery latent phase, meconium staining, uterine hypertonisity and apgar score (1&5 minute) were similar in two groups. Conclusion: sublingual Misoprostol is better than intravenous Oxytocin for induction of labor at term. https://jfrh.tums.ac.ir/index.php/jfrh/article/view/151 https://jfrh.tums.ac.ir/index.php/jfrh/article/download/151/151