The Effect of Cervical Canal Cleaning Before IUI in Infertile Couples
Abstract
Objective: Intrauterine insemination (IUI) is known as a routine method for infertility treatment. The effectiveness of IUI is not identical in all cases. So in this study to evaluate different methods of IUI in order to increase pregnancy rate, IUI with cleaning cervical canal by swab is compared to IUI without cervical canal cleaning.
Material and methods: This study was conducted from 2008/2/1 to 2008/9/30 in MirzaKochak Khan Infertility center. Totally 224 cases were selected for IUI divided into two groups. Group one (n=112) had cervical cleaning with swab before IUI and group two (n=112) was control group. Pregnancy rate were compared in two groups.
Results: Two groups were matched regarding age, type of infertility and number of follicles. Pregnancy rate in cervical canal cleaning (group one) and control group (group two) was 15.1% and 9.8% respectively. The difference was not significant.
Conclusion: In this study with cleaning cervical canal by swab before IUI there was a non-significant increase in pregnancy rate.
Speroff L, Fritz MA. Clinical Gynecologic Endocrinology & Infertility, 2005, 7 th ed, Vol 2, page 1023–1026. Wilkins: Philadelphia: Lippincott and Williams.
Helmerhorst FM, Van Vliet HA, Gornas T, Finken MJ, Grimes DA. Intra–uterine insemination versus timed intercourse or expectant management for cervical hostility in subfertile couples. Cochrane Database Syst Rev 2005; 19: CD002809.
Hughes EG.The effectiveness of ovulation induction and intrauterine insemination in the treatment of persistent infertility: a meta–analysis.Human Reproduction 2000, Vol 12, 1865–1872.
Do Amaral VF, Ferriani RA, Dos Reis RM, De Sala MM, De Moura MD. Effect of inseminated volume on intrauterine insemination. Journal Assist Reproductive Genetic 2001; 18: 413–6.
Smith KL, Grow DR, Wiczyk HP, O'Shea DL, Arny M. Does Catheter Type Effect Pregnancy Rate in Intrauterine Insemination Cycles? Journal of Assisted Reproduction and Genetics 2002; 19: 49–52.
Zeyneloglu HB, Bagis T. Lembet A, Ergin T, Kuscu E. Double IUI in clomiphene citrate cycles do not provide any advantage over single IUI: A randomized controlled trial. Fertil Steril.2002; 78: Suppl1: S55.
Ragni G,somigliana E, vegetti W. Timing of intrauterine insemination: where we are? Fertility sterility 2004; 82: 25–6.
Katz DF. Human cervical mucus: research update. American Journal Obstetric Gynecology 1991; 165: 1984–6.
Mansour RT, Aboulghar MA. Optimizing the embryo transfer technique. Human Reproductive 2002; 17: 1149–53.
Eskandar MA, Abou–Setta AM, El–Amin M, Almushait MA, Sobande AA. Removal of cervical mucus prior to embryo transfer improves pregnancy rates in women undergoing assisted reproduction. Reproductive Biomedical Online 2007; 14: 308–13.
Berkkanoglu M, Isikoglu M, Seleker M,Ozgur K. Flusing the endometrium prior to the embryo transfer dose not affect the pregnancy rate. Reproductive Biomedical Online 2006; 13: 268–71.
Simsek E, Haydardedeoglu B, Hacivelioglu SO, Cok T, Parlakgumus A, Bagis T. Effect of cervical mucus aspiration before intrauterine insemination. Internal Journal Gynaecology Obstetric 2008; 103: 136–9.
Fanchin R, Harmas A, Benaoudia F, Lundkvist U, Olivennes F, Frydman R. Microbial flora of the cervix assessed at the time of embryo transfer adversely affects in vitro fertilization outcome. Fertility Sterility 1998; 70: 866–70.
Oei SG, Helmerhorst FM, Bloemenkamp KW, Hollants FA, Meerpoel DE, Keirse MJ. Effectiveness of post coital test:A randomized controlled trail. Biomedical Journal 1998; 317: 502–5.
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Issue | Vol 4, No 2 (June 2010) | |
Section | Original Articles | |
Keywords | ||
cervical canal aspiration cervical canal cleaning IUI ovulation induction unexplained infertility |
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