Original Articles

Body Mass Index and success rate of IVF

Abstract

Objective: This study investigated the effect of body mass index (BMI) on the success rate of IVF for couples with different causes of infertility.
Materials and methods: In a cross sectional descriptive- analytic study conducted simultaneously in Mehr IVF center and Vali-e-Asr Reproductive Health Research Center, the success rate of IVF was examined in 396 consecutive women undergoing IVF cycles. Clinical pregnancy rate per first cycle of IVF was evaluated with regard to BMI. SPSS 11 software was used for statistical analyses. Significance level was identified as P< 0.05 in data analysis.
Results: Women with a BMI of 27 kg/m2 had a significantly lower pregnancy rate compared with normal weight women (BMI 20 and <27 kg/m2), OR = 0.67 (95% CI 0.48-0.94).For male infertility the rate of pregnancy per cycle was significantly lower than unexplained infertility, OR = 0.70 (95% CI 0.57-0.86.) For tubal pathology the rate was slightly lower than unexplained infertility, OR = 0.86 (95% CI 0.70-1.01).
Conclusion: Overweight unfavorably affects the pregnancy rate after IVF. Infertile couples may improve the outcome of IVF treatment by lifestyle changes.

-Steptoe PC, Edwards RG. Birth after the reimplantation of a human embryo.Lancet 1978; 2(8085): 366.

-Alsalili M, Yuzpe A, Tummon I, Parker J, Martin J, Daniel S,et al. Cumulative pregnancy rates and pregnancy outcome after in-vitro fertilization: > 5000 cycles at one centre. Hum Reprod 1995; 10(2): 470-474.

-Tan SL, Royston P, Campbell S, Jacobs HS, Betts J, Mason B, Edwards RG. Cumulative conception and livebirth rates after in-vitro fertilisation. Lancet 1992; 339(8806): 1390-1394.

-Templeton A, Morris JK, Parslow W. Factors that affect outcome of in-vitro fertilisation treatment. Lancet 1996; 348(9039): 1402-1406.

-Smeenk JM, Stolwijk AM, Kremer JA, Braat DD. External validation of the templeton model for predicting success after IVF. Hum Reprod 2000; 15(5): 1065-1068.

- Norman RJ, Clark AM. Obesity and reproductive disorders: a review.Reprod Fertil Dev 1998; 10(1): 55-63.

-Wang JX, Davies M, Norman RJ. Body mass and probability of pregnancy during assisted reproduction treatment: retrospective study.BMJ 2000 25; 321(7272): 1320-1321.

-Wang JX, Davies MJ, Norman RJ. Obesity increases the risk of spontaneous abortion during infertility treatment. Obes Res 2002; 10(6): 551-554.

-Nichols JE, Crane MM, Higdon HL, Miller PB, Boone WR. Extremes of body mass index reduce in vitro fertilization pregnancy rates. Fertil Steril 2003; 79(3): 645-647.

-Johnson NP, Mak W, Sowter MC. Laparoscopic salpingectomy for women with hydrosalpinges enhances the success of IVF: a Cochrane review. Hum Reprod 2002; 17(3): 543-548.

-Haan G, Bernardus RE, Hollanders JM, Leerentveld RA, Prak FM, Naaktgeboren N. Results of IVF from a prospective multicentre study. Hum Reprod 1991; 6(6): 805-810.

-Kremer JA, Beekhuizen W, Bots RS, Braat DD, van Dop PA, Jansen CA, et al. [Results of in vitro fertilization in the Netherlands, 1996-2000] Ned Tijdschr Geneeskd 2002; 146(49): 2358-2363.

-de Mouzon J, Rossin-Amar B, Bachelot A, Renon C, Devecchi A. FIVNAT. Influence of attempt rank in in vitro fertilization] Contracept Fertil Sex 1998; 26(7-8): 466-472.

-Haan G, Bernardus RE, Hollanders HM, Leerentveld BA, Prak FM, Naaktgeboren N. Selective drop-out in successive in-vitro fertilization attempts: the pendulum danger. Hum Reprod 1991; 6(7): 939-943.

-De Vries MJ, De Sutter P, Dhont M. Prognostic factors in patients continuing in vitro fertilization or intracytoplasmic sperm injection treatment and dropouts. Fertil Steril 1999; 72(4): 674-678.

-Land JA, Courtar DA, Evers JL. Patient dropout in an assisted reproductive technology program: implications for pregnancy rates. Fertil Steril 1997; 68(2): 278-281.

Files
IssueVol 1, No 1 (September 2007) QRcode
SectionOriginal Articles
Keywords
Body Mass Index IVF pregnancy rate infertility diagnosis

Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
How to Cite
1.
Savadkouhi F, Jafarabadi M, Ramezanzadeh F. Body Mass Index and success rate of IVF. J Family Reprod Health. 2007;1(1):41-46.