Effect of Exposure to Air Pollution on Placental Weight in Isfahan-Iran

  • Hatav Ghasemi Tehrani Department of Obstetrics and Gynecology, Isfahan University of Medical Sciences, Isfahan, Iran
  • Setare Fallah Isfahan University of Medical Sciences, Isfahan, Iran
  • Nafiseh Mozafarian Department of Pediatrics, Child Growth and Development Research Center, Research Institute for Primordial Prevention of Non-Communicable Diseases, Isfahan University of Medical Sciences, Isfahan, Iran
  • Sareh Miranzadeh Child Growth and development Research Center, Research Institute for Primordial Prevention of Non – Communicable Diseases, Isfahan, Iran
  • Shokooh Sadeghi Department of Anesthesia, Shahid Beheshti Hospital, Isfahan, Iran
  • Azam Azidhak Department of Obstetrics and Gynecology, Shahid Beheshti Hospital, Isfahan, Iran
Air Pollution, Pregnancy Outcomes, Birth Weight, Placental Weight


Objective: To determine the effect of Air Quality Index (AQI) in the first trimester of pregnancy on birth weight, placental weight, and the ratio of placental weight to the birth weight (pw-bw) in Isfahan.Materials and methods: This cross-sectional study was done on 312 consecutive pregnant women in Beheshti Hospital in Isfahan city in 2013. Information on air pollution was received from the Environmental department of Isfahan. Average exposure to air pollution in the first trimester of pregnancy was calculated for eachpregnant woman. In order to compare quantitative and qualitative variables, analysis of variance (ANOVA), and chi-square were applied. After that, the multiple linear regression analysis was used to assess the association the Air Quality Index (AQI) on birth weight, placental weight and the ratio of pw-bw. Potential confounders including age, baby gender, smoking of husband, maternal BMI, maternal occupation, and education and mother’s residential area were considered. A statistical significant association were considered for P-value less than 0.05.Results: The findings showed that there is inverse relationship between exposure to air pollution and placental weight in the first trimester of pregnancy after controlling potential confounders (β = -2.57, p-value = 0.008). The inverse relationship between air pollution and the ratio of pw-bw was found. (β = -0.001, p-value = 0.002).Conclusion: The results of this study suggest that air pollution is associated with newborns’ health which in turn is a warning alarm for considering some actions in both sides of reducing the air pollution and teaching the pregnant women about the adverse effects of air pollution on the pregnancy outcomes.


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How to Cite
Ghasemi Tehrani H, Fallah S, Mozafarian N, Miranzadeh S, Sadeghi S, Azidhak A. Effect of Exposure to Air Pollution on Placental Weight in Isfahan-Iran. J Fam Reprod Health. 11(2):90-96.
Original Articles