Group B Streptococcus Positive Culture’s Results in Pregnants with Preterm Premature Rupture of Membranes
AbstractObjective: Preterm premature rupture of membranes (PPROM) occurs in 2% of all pregnancies. The aim of this study was to compare positive cultures of GBS in two groups of pregnant women.Materials and methods: This case control research was conducted on 242 pregnant women: first group was consisted of 117 pregnant with PPROM and gestational ages between 26-37 weeks; second group was consisted of 125 term pregnant women with intact membranes and before onset of labor. Rectovaginal and urine samples were studied using specific culture medium of GBS, "Todd Hewitt Broth". The percentage of positive results was calculated using odds ratio and chi-square test.Results: GBS cultures were positive in 20 cases (17%) in PPROM group and 5 cases in group of term pregnant (4%) (Odds ratio=4.95 CI= 1.79-13.67, p=0.001). Past history of preterm labor and neonate hospitalization were more common in PPROM group but without any significant relationship to positive cultures.Conclusion: Our study showed significant difference of GBS colonization rate between two groups (p=0.001). According to CDC and ACOG guidelines routine screening and treatment of positive cases are indicated.
Svigos JM, Robinson JS, Vigneswaran R. Premature rupture of the membranes in pregnancy. In: James DK, Steer PJ, Weiner CP, Gonik B, eds. High risk pregnancy management options. Philadelphia: WB Saunders, 2006: 1321-8.
Feikin DR, Thorsen P, Zywicki S, Arpi M, Westergaard JG, Schuchat A. Association between colonization with group B streptococci during pregnancy and preterm delivery among Danish women. Am J Obstet Gynecol 2001; 84 : 427-33.
Sweet RL, Gibbs RS. Infectious disease of the female genital tract. Fourth ed. Philadelphia: Lippincott Williams Wilkins, 2002: 501-3.
Prevention of prenatal group B streptococcal disease: a public health perspective. Centers for Disease Control and Prevention. MMWR 1996; 45: 1–24.
Thompson TR. Group B streptococcal Infections: MMWR Recomm Rep 1 (R-11) 2002: 1-23.
Cunningham FG, Leveno KJ, Bloom SL, Hauth JC, Gilstrap LC, Wenstrom KD. Williams Obstetrics. New York: Mc Graw – Hill, 2005: 213, 1285.
Winn HN, Hamill TT. Group B streptococcus infection. In: Winn HN, Hobbins JC, eds. Clinical maternal- fetal medicine. New York: parthenon publishing, 2000: 209.
Klein LL, Gibbs RS. Use of microbial cultures and antibiotics in the prevention of infection associated preterm birth. Am J of Obstet Gynecol 2004; 190 (6): 1493-1502.
Copyright (c) Journal of Family and Reproductive Health
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.