Original Articles

Sexual Function and Quality of Life in Iranian Women With Human Papillomavirus Infection

Abstract

Objective: Considering the prevalence of Human Papillomavirus (HPV) infection and the lack of HPV vaccination program in Iran among young women and the importance of quality of life and sexual performance in women, we decided to conduct a study to examine the relationship between HPV infection and sexual dysfunction and quality of life in Iranian women.
Materials and methods: In this cohort study, 250 married women who infected with HPV were recruited via convinence sampling from colposcopy clinic of Arash women hospital (Tehran, Iran) from April 2020 to May 2022.They were evaluated concerning their sexual function in the domains of desire, arousal, lubrication, orgasm, satisfaction and pain with the female sexual function index (FSFI) questionnaire (the total FSFI score is calculated by the sum of the nineteen items). Sexual quality of life-female (SQOL-F) items (Likert-type scale with a cut-off of 65 points) were organized into four sub-scales: psychosexual feelings, sexual and relationship satisfaction, self-worthlessness, and sexual repression. All patients filled out the female sexual function index (FSFI) and sexual quality of life (SQOL) questionnaires. Variables were analysed via correlation coefficient and linear regression tests.
Results: Mean age and mean marriage duration were 38.5±4.5 and 12.2±7.2, respectively. There was a weak correlation between FSFI and SQOL (r=0.15, p=0.001).Time of marriage and genital warts were the predictors on the FSFI and SQOL.
Conclusion: The findings suggest that HPV infection can impair sexual function and quality of life. This research contributes valuable insights, especially considering the prevalence of HPV.

1. Kombe Kombe AJ, Li B, Zahid A, Mengist HM, Bounda GA, Zhou Y, et al. Epidemiology and Burden of Human Papillomavirus and Related Diseases, Molecular Pathogenesis, and Vaccine Evaluation. Front Public Health. 2021;8:552028.
2. Zang L, Hu Y. Risk factors associated with HPV persistence after conization in high-grade squamous intraepithelial lesion. Arch Gynecol Obstet. 2021;304(6):1409-1416.
3. Fornage S, Schweizer A, Lepigeon K, Bianchi Demicheli F, Faouzi M, Jacot-Guillarmod M. Is women's sexual function impaired by an abnormal pap smear? Eur J Contracept Reprod Health Care. 2022 Jun;27(3):184-188.
4. Omani-Samani R, Amini P, Navid B, Sepidarkish M, Maroufizadeh S, Almasi-Hashiani A. Prevalence of sexual dysfunction among infertile women in Iran: a systematic review and meta-analysis. International journal of fertility & sterility. 2019;12(4):278.
5. Mobini Kesheh M, Keyvani H. The Prevalence of HPV Genotypes in Iranian Population: An Update. Iran
J Pathol. 2019;14(3):197-205.
6. Lewandowski P, Lipowska K, Magda I. The gender dimension of occupational exposure to contagion in Europe. Feminist Economics. 2021;27(1-2):48-65.
7. Coronado PJ, González-Granados C, Ramírez-Mena M, Calvo J, Fasero M, Bellón M, et al. Development and psychometric properties of the human papillomavirus-quality of life (HPV-QoL) questionnaire to assess the impact of HPV on women health-related-quality-of-life. Arch Gynecol Obstet. 2022;306(4):1085-1100.
8. Graziottin A, Serafini A. HPV infection in women: psychosexual impact of genital warts and intraepithelial lesions. J Sex Med. 2009;6(3):633-45.
9. Lin H, Jeng CJ, Wang LR. Psychological responses of
women infected with cervical human papillomavirus: A qualitative study in Taiwan. Taiwan J Obstet Gynecol. 2011;50(2):154-8.
10. Arrossi S, Almonte M, Herrero R, Gago J, Sánchez Antelo V, Szwarc L, et al. Psycho-social impact of positive human papillomavirus testing in Jujuy, Argentina results from the Psycho-Estampa study. Prev Med Rep. 2020;18:101070.
11. Chadwick V, Bennett KF, McCaffery KJ, Brotherton JML, Dodd RH. Psychosocial impact of testing human papillomavirus positive in Australia's human papillomavirus-based cervical screening program: A cross-sectional survey. Psychooncology. 2022;31(7):1110-1119.
12. Fakhri A, Pakpour AH, Burri A, Morshedi H, Zeidi IM. The Female Sexual Function Index: translation and validation of an Iranian version. J Sex Med. 2012;9(2):514-23.
13. Maasoumi R, Lamyian M, Montazeri A, Azin SA, Aguilar-Vafaie ME, Hajizadeh E. The sexual quality of life-female (SQOL-F) questionnaire: translation and psychometric properties of the Iranian version. Reprod Health. 2013;10:25.
14. Wiegel M, Meston C, Rosen R. The female sexual function index (FSFI): cross-validation and development of clinical cutoff scores. J Sex Marital Ther. 2005;31(1):1-20.
15. Roshan Chesli R, Soleimani Z, Erfan T, Mantashlou S, Hashemi A. Evaluate the psychometric properties of sexual quality of life questionnaire (SQOL-F). Clinical Psychology and Personality. 2020;17(1):213-24.
16. Nahidi M, Nahidi Y, Kardan G, Jarahi L, Aminzadeh B, Shojaei P, et al. Evaluation of Sexual Life and Marital Satisfaction in Patients with Anogenital Wart. Actas Dermosifiliogr (Engl Ed). 2019;110(7):521-525. English, Spanish.
17. Nia MH, Rahmanian F, Ghahartars M, Janghorban R. Sexual function and sexual quality of life in men with genital warts: a cross-sectional study. Reprod Health. 2022;19(1):102.
18. Sakin Ö, Uzun SB, Koyuncu K, Giray B, Akalın EE, Anğın AD. Cervix human papilloma virus positivity: Does it cause sexual dysfunction? Turk J Obstet Gynecol. 2019;16(4):235-241.
19. Aker SŞ, Ağar E, Tinelli A, Hatirnaz S, Ortaç F. The Impact of HPV Diagnosis and Abnormal Cervical Cytology Results on Sexual Dysfunction and Anxiety. Int J Environ Res Public Health. 2023;20(4):3630.
20. Gürkan N, Gürbüz T. The Relationship between Human Papillomavirus and Anxiety, Depression, and Sexual Dysfunction in Women. Journal of Experimental and Clinical Medicine. 2022;39(4):999-1003.
21. Mercan R, Mercan S, Durmaz B, Sur H, Kilciksiz CM, Kacar AS, et al. Sexual dysfunction in women with human papilloma virus infection in the Turkish population. J Obstet Gynaecol. 2019;39(5):659-663.
22. Eftekhar T, Sohrabvand F, Zabandan N, Shariat M, Haghollahi F, Ghahghaei-Nezamabadi A. Sexual dysfunction in patients with polycystic ovary syndrome and its affected domains. Iran J Reprod Med. 2014;12(8):539-46.
23. Eftekhar T, Dashti M, Shariat M, Haghollahi F, Raisi F, Ghahghaei-Nezamabadi A. Female sexual function during the menopausal transition in a group of Iranian women. Journal of family & reproductive health. 2016;10(2):52.
24. Uzun SB, Sakin Ö, Çetin H, Şimşek EE. The Effects of HPV Test on Anxiety, Emotion and Depression in Women. Journal of Academic Research in Medicine. 2020;10(2).
25. Sweileh WM, Zyoud SH, Abu Nab'a RJ, Deleq MI, Enaia MI, Nassar SM, et al. Influence of patients' disease knowledge and beliefs about medicines on medication adherence: findings from a cross-sectional survey among patients with type 2 diabetes mellitus in Palestine. BMC Public Health. 2014;14:94.
26. Eser A, Aker SŞ. The effects of anogenital condylomas on female sexuality and psychology: a case-control study. Journal of health sciences and medicine. 2021;4(4):482-7.
Files
IssueVol 18, No 3 (September 2024) QRcode
SectionOriginal Articles
DOI https://doi.org/10.18502/jfrh.v18i3.16656
Keywords
Sexual Dysfunctions Human Papillomavirus (HPV) Quality of Life
Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
How to Cite
1.
Tehranian A, Vahid Dastjerdi M, Hatamian S, Ghahghaei-Nezamabadi A. Sexual Function and Quality of Life in Iranian Women With Human Papillomavirus Infection. J Family Reprod Health. 2024;18(3):154-159.