Molar Changes With a Normal Viable Fetus: A Case Report
Abstract
Objective: The presence of a normal fetus with normal karyotype accompanied by molar changes in the placenta is a rare condition, which carries a significant risk to the mother and fetus. There is a controversy regarding the proper management of this condition. Here, we present the case of a singleton pregnancy that showed molar changes in the pathological study of the placenta, but ended up with a normal viable neonate.
Case Report: A 23-year-old primigravida woman, with a 3-year history of infertility, presented with vaginal bleeding and spotting. Her ß-human chorionic gonadotropin (HCG) at 13th week was 36500 mIU/ml. Serial sonography assessments were suggestive for molar changes and a normal fetus with growth retardation but normal Doppler assessment. The patient underwent elective Cesarean section at 37 weeks gestation and a healthy female neonate with an Apgar score of 9-10, weighing 2270 g was born. Pathological assessment of the placenta confirmed the diagnosis of incomplete hydatidiform mole. After two months, the mother had no complications, her ß-HCG level was untraceable, and the infant was in good condition.
Conclusion: Despite being a rare condition, partial moles can be accompanied by delivery of a normal fetus. The management of this condition still remains challenging and should be done under close monitoring with extreme caution.
2. Eagles N, Sebire NJ, Short D, Savage PM, Seckl MJ, Fisher RA. Risk of recurrent molar pregnancies following complete and partial hydatidiform moles. Hum Reprod 2015; 30: 2055-63.
3. Lurain JR. Hydatidiform mole: Recognition and management. Contemporary OB/GYN 2019; 64: 12-7.
4. Tesemma MG. Singleton Partial Molar Pregnancy Delivered in Third Trimester: A Case Report. Journal
of Patient Care 2019; 5: 1.
5. Sebire NJ, Foskett M, Paradinas FJ, Fisher RA, Francis RJ, Short D, et al. Outcome of twin pregnancies with complete hydatidiform mole and healthy co-twin. Lancet 2002; 359: 2165-6.
6. Vejerslev LO, Sunde L, Hansen BF, Larsen JK, Christensen IJ, Larsen G. Hydatidiform mole and fetus with normal karyotype: support of a separate entity. Obstet Gynecol 1991; 77: 868-74.
7. Giorgione V, Cavoretto P, Cormio G, Valsecchi L, Vimercati A, De Gennaro A, et al. Prenatal Diagnosis of Twin Pregnancies with Complete Hydatidiform Mole and Coexistent Normal Fetus: A Series of 13 Cases. Gynecologic and obstetric investigation 2017; 82: 404-9.
8. Bruchim I, Kidron D, Amiel A, Altaras M, Fejgin M. Complete hydatidiform mole and a coexistent viable fetus: report of two cases and review of the literature. Gynecologic oncology 2000; 77: 197-202.
9. Deveer R, Ustun YE, Eryilmaz OG, Akbaba E, Deveer M. Molar Pregnancy with a Co-Existing Viable Fetus. J Clin Anal Med 2015; 6: 88-90.
10. Rahamni M, Parviz S. A case report of partial molar pregnancy associated with a normal appearing dizygotic fetus. Asian Pacific J Reprod 2016; 5: 171-3.
11. Abukaftah A, Jabeen S, Moawad A, Almetrek M. A Case Report of Partial Molar Pregnancy Associated with A Normal Dizygotic Twin.The Egyptian Journal of Hospital Medicine. 2018; 70: 1221-3.
12. Guvendag Guven ES, Ozturk N, Deveci S, Hizli D, Kandemir O, Dilbaz S. Partial molar pregnancy and coexisting fetus with diploid karyotype. J Matern Fetal Neonatal Med 2007; 20: 175-81.
| Files | ||
| Issue | Vol 14, No 3 (September 2020) | |
| Section | Case Reports | |
| DOI | https://doi.org/10.18502/jfrh.v14i3.4675 | |
| Keywords | ||
| Incomplete Hydatidiform Mole Normal Fetus Fetal karyotype | ||
| Rights and permissions | |
|
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License. |
