Ibuprofen Versus Fennel for the Relief of Postpartum Pain: A Randomized Controlled Trial
AbstractObjective: The present study aimed to compare the value of ibuprofen and fennel for postpartum painrelief in women with normal vaginal delivery.Materials and methods:In this randomized clinical trial we studied 90 women referring to obstetrics ward for Normal Vaginal Delivery (NVD) in Assali hospital in Khoramabad. Women were randomly allocated to receive either oral ibuprofen or oral fennel by stratified random sampling technique. All women were asked to give pain score by visual analogue scale before and at 1, 2, 3 and 4 hours after treatment.Results: Difference between fennel and ibuprofen groups was not significant considering severity of pain before (P=0.22). Difference between two groups considering mean severity of pain one hour after treatment (P=0.57) was not significant. But comparing the mean of pain severity in two groups, showed significant difference after two (p<0.023), three (p<0.001) and four (p<0.001) hours after treatment.Conclusion: Ibuprofen and fennel were effective for relief of postpartum pain without any notable side effects, but in general ibuprofen was more effective than fennel. More studies are needed to confirm the efficacy of fennel in pain relief especially in postpartum women which must be compared to a no treatment control group.
Cunningham F. leveno KJ, Bloom SL, Hauth JC, Gilsraplli LC, Wensstrom KD: Williams obstet. 23th ed;New York ,MC Graw –Hill 2010 : 647-648.
Briggs GG, Freeman RK, Yaffe SJ. Ibuprofen. In: Briggs GG, Freeman RK, Yaffe SJ, editors. Drugs in pregnancy and lactation. 7th ed. Philadelphia: Lippincott Williams & Wilkins; 2005: 800-4.
Compendium of pharmaceuticals and specialties. 35th ed. Ottawa: Canadian Pharmaceutical Association; 2000.
Kamondetdecha R, Tannirandorn Y. Ibuprofen versus acetaminophen for the relief of perineal pain after childbirth: a randomized controlled trial. J Med Assoc Thai 2008; 91: 282-6.
Stary F,J irasck VA. Concise Guide in Colour Herbs. Hamlyn; London, New York, Sydney, Toronto; 1975.
Ruberto G, Baratta MT, Deans SG, Dorman HJ. Antioxidant and antimicrobial activity of Foeniculum vulgare and Crithmum maritimum essential oils. Planta Medico2000; 66:687-93.
Alexandrovich I, Rakovitskaya O, Kolmo E, Sidorova T, Shushunov S. The effect of fennel (Foeniculum Vulgare) seed oil emulsion in infantile colic: a Randomized, placebo-controlled study. Altern Ther Health Med. 2003; 9:58-61.
Namavar Jahromi B, Tartifizadeh A, Khabnadideh S. Comparison of fennel and mefenamic acid for the treatment of primary dysmenorrhea. Int J Gynaecol Obstet 2003; 80:153-7.
Skovlund E, Fyllingen G, Landre H, Nesheim BI. Comparison of postpartum pain treatments using a sequential trial design. I. Paracetamol versus placebo. Eur J Clin Pharmacol 1991; 40:343-7.
Peter EA. A cost-utility evaluation of post-operative analgesia in the elderly in acommunity hospital using decision analysis. Can J Anaesth 1994; 41:22.
ModaressNejad V, AsadipourM.Comparison of the effectiveness of fennel and mefenamic acid on pain intensity in dysmenorrhoea. East Mediterr Health J. 2006; 12(3-4): 423-7.
Manochehri Tarshizi E, MontazeriS,Abdi P. Comparison of the effect of fennel and Ibuprofen on primary dysmenorrhealin high school students Medical Science Journal of Islamic Azad University of Mashhad 2005; 3: 17-24.
Porter EA, Janssen PA, Grange CS, Douglas MJ. Ibuprofen versus acetaminophen with codeine for the relief of perineal pain after childbirth: a randomized controlled trial. CM AJ 2001; 165:1 203-9.
Schachtel BP, Thoden WR, Baybutt RI. Ibuprofen and acetaminophen in the relief of postpartum episiotomy pain. J Clin Pharmacol 1989 Jun; 29:550-3.
Behotas S, Chauvin A, Castiel J, Martin A, BoureauF, Barrat J, et al. [Analgesic effect of ibuprofenin pain after episiotomy]. Ann FrAnesth Reanim 1992; 11: 22-6.