Predictors of Preeclampsia Based on a 10-Year Case-Control Study

  • Arezoo Shayan Mother and Child Care Research Center, Hamadan University of Medical Sciences, Hamadan, Iran
  • Hadis Sourinezhad School of Nursing and Midwifery, Hamadan University of Medical Sciences, Hamadan, Iran
  • Mansoureh Refaei Mother and Child Care Research Center, Hamadan University of Medical Sciences, Hamadan, Iran
  • Seyedeh Zahra Masoumi Mother and Child Care Research Center, Hamadan University of Medical Sciences, Hamadan, Iran
  • Leili Tapak Department of Biostatistics, School of Public Health, Hamadan University of Medical Sciences, Hamadan, Iran
  • Farzaneh Soltani Mother and Child Care Research Center, Hamadan University of Medical Sciences, Hamadan, Iran
Preeclampsia, Prediction, Seasonal Changes, Blood Group


Objective: To investigate the predictors of preeclampsia based on a 10-years case-control study. Materials and methods: The present retrospective, case-control study was carried out in a referral Hospital in Hamadan, Iran, during 2005-2015. Using a hospital information system (HIS), all the available information on hospitalized preeclamptic patients during 10-years period was collected and all preeclamptic women were qualified for the study as the case group (729 subjects) and the same number of non-preeclamptic women were assigned to the control group. The required data were collected using the researcher-made questionnaire and analyzed using descriptive statistics, chi-square test, independent t-test and logistic regression.Results: The results show that high age (OR = 1.04), low education (diploma compared to illiterate OR = 0.51 and middle school education compared to illiterate OR = 0.55), blood group O (AB: OR = 0.32; B: OR = 0.36; A: OR = 0.26) and fertilization during autumn (spring: OR = 0.41; summer: OR = 0.26; autumn: OR = 1.13) could raise the risk of preeclampsia.Conclusion: High age, low education, blood group O and fertilization in cold seasons could be the risk factors of preeclampsia. Recognizing the risk factors of preeclampsia could help the determination of high risk cases and designing of effective interventions.


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How to Cite
Shayan A, Sourinezhad H, Refaei M, Masoumi SZ, Tapak L, Soltani F. Predictors of Preeclampsia Based on a 10-Year Case-Control Study. J Fam Reprod Health. 13(1):14-20.
Original Articles