Management of Adenocarcinoma In Situ of Cervix in Pregnancy

  • Alireza Abidi Department of Obstetrics and Gynecology, Bridgeport Hospital, Yale New Haven Bridgeport University, CT
  • Ali Hamraz Department of Gynecologic Oncology, Yale School of Medicine, New Haven, CT
  • Masoud Azodi Department of Obstetrics and Gynecology, Bridgeport Hospital, Yale New Haven Bridgeport University,
Keywords: AIS, CIS, Pregnancy

Abstract

Adenocarcinoma in situ is one of the premalignant lesions of the cervix and its incidence is believed to be increasing while the pathogenesis of the disease is not clearly understood. Management of Adenocarcinoma in situ (AIS) unlike carcinoma in situ (CIS) has not been clearly described in the current literature. Here we describe conservative management and serial  olposcopy of two pregnant women with adenocarcinoma in situ of the cervix. Both of the cases were diagnosed initially with abnormal Pap smears and were confirmed by colposcopic directed biopsy. None of the patients agreed with any invasive procedure during pregnancy and both of them were followed with serial colposcopy. None of the lesions showed any evidence of progression. All cases underwent cold knife cone biopsies in their postpartum period. Hysterectomy as the final treatment has been done in both cases with no evidence of progression of the disease during pregnancy. We concluded that adenocarcinoma in situ of the  cervix during pregnancy could be managed conservatively with definite treatment postponed till after delivery.

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How to Cite
1.
Abidi A, Hamraz A, Azodi M. Management of Adenocarcinoma In Situ of Cervix in Pregnancy. J Fam Reprod Health. 2(1):53-57.
Section
Case Reports