Tehran University of Medical Sciences Journal of Family and Reproductive Health 1735-8949 15 4 2021 11 28 220 228 EN Fatemeh Modiri Department of Family Studies, National Institute for Population Research, Tehran, Iran Rasoul Sadeghi Department of Family Studies, National Institute for Population Research, Tehran, Iran AND Department of Demography, Faculty of Social Sciences, University of Tehran, Tehran, Iran 2021 03 09 2021 09 11 Objective: Changes in the gendered division of domestic labour are often assumed to influence childbearing intention, but existing evidence is varied and less examined in the Asian context. This paper aims to investigate the association between the gendered division of domestic labour and the intention to have another child. Materials and methods: A cross-sectional survey was conducted in Tehran on 455 married women aged 18-40 years who were selected through a multi-stage cluster sampling. Results: Domestic labour is still a feminine role and the majority of women are satisfied with the division of domestic labour. Women’s satisfaction with the division of domestic labour is a predictor of their tendency to have another child, but the actual division of domestic labour has not a significant effect on women’s desire to childbearing, in the multivariate model. Conclusion: Women’s desire for having another child is positively impacted by their satisfaction with the gendered division of labour in their household. To achieve more fertility, gender equality in the family and identifying the factors affecting women's satisfaction with the division of domestic labour is suggested. https://jfrh.tums.ac.ir/index.php/jfrh/article/view/1724 https://jfrh.tums.ac.ir/index.php/jfrh/article/download/1724/577

Tehran University of Medical Sciences Journal of Family and Reproductive Health 1735-8949 15 4 2021 11 28 258 261 Reza Khadivi Community Medicine Department, Medical School, Isfahan University of Medical Sciences, Isfahan, Iran Mahshid Nagi Community Medicine Department, Medical School, Isfahan University of Medical Sciences, Isfahan, Iran Asefe Haddadpoor Information Technology Group, Provincial Health Center, Isfahan, Iran 2021 02 25 2021 06 26 Objective: The present study aimed to determine the prevalence of anti-syphilis antibodies in Iranian pregnant women who attended antenatal care (ANC) in 21 districts affiliated to Isfahan University of Medical Sciences (MUI) from April 2017 to April 2020. Materials and methods: In a cross-sectional study in 2020, the data about anti syphilis antibody were collected from electronic health files of pregnant women. Pregnancy specific health package was delivered to Iranian pregnant women in a horizontally integrated network across the country. The electronic health file was used for every Iranian citizen and all health events were recorded by their health care providers in 2016. All health services, particularly laboratory tests that were performed either in public or private laboratories, that were given to pregnant women needed to be recorded in their electronic health files. According to the pregnancy health package, they were screened initially by Rapid Plasma Reagin (RPR) test. Results: In those years, 70512, 72298, 63272 pregnant women were screened respectively. In these intervals, using the RPR test, no positive cases of anti- syphilis antibody were found. Conclusion: It seems that syphilis infection among Iranian pregnant women who attended ANC in districts affiliated to MUI has reached the elimination phase. https://jfrh.tums.ac.ir/index.php/jfrh/article/view/1714 https://jfrh.tums.ac.ir/index.php/jfrh/article/download/1714/582

Tehran University of Medical Sciences Journal of Family and Reproductive Health 1735-8949 15 4 2021 11 28 262 265 Nahathai Paktinun Bumrungrad International Hospital, Bangkok, Thailand Chartchai Srisombut Bumrungrad International Hospital, Bangkok, Thailand Thidarat Kongwattanasin Bumrungrad International Hospital, Bangkok, Thailand Krit Pongpirul Bumrungrad International Hospital, Bangkok, Thailand AND Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand AND Johns Hopkins Bloomberg School of Public Health, Baltimore, USA 2021 01 07 2021 08 17 Objective: Sperm donation and hormonal therapy with micro-Testicular Epididymal Sperm Extraction (TESE) for infertility from testicular failure might not always be available in some contexts. We report a successful embryo transfer from the patient-by ‘cumulative sperm collection’ strategy. Case report: A 42 year-old male presented with non-obstructive azoospermia from testicular failure. Hormonal treatments were given along with the patient-initiated ‘cumulative sperm collection’ strategy, which eventually resulted in 17 sperms retrieved. Twelve mature oocytes were selected for intracytoplasmic sperm injection (ICSI) with the retrieved sperms, of which 8 oocytes were successfully fertilized but only two reached the early blastocyst stage; the first embryo transfer was not successful. Another five eggs were thawed and fertilized with the remaining 5 sperms and 3 oocytes were successfully fertilized: Seven cells were grade 3, 6 cells were grade 3, and 3 cells were grade 3. The second embryo transfer was successful, and the term female infant was successfully delivered by cesarean section. Conclusion: At a center without micro-TESE availability, successful embryo transfer for testicular failure type IV could be achieved by hormonal therapy plus a ‘cumulative sperm collection’ strategy. https://jfrh.tums.ac.ir/index.php/jfrh/article/view/1668 https://jfrh.tums.ac.ir/index.php/jfrh/article/download/1668/583

Tehran University of Medical Sciences Journal of Family and Reproductive Health 1735-8949 15 4 2021 11 28 229 235 Shokoh Abotorabi Department of Obstetrics and Gynecology, Clinical Research Development Unit, Kosar Hospital, Qazvin University of Medical Sciences, Qazvin, Iran Solmaz Chamanara Department of Obstetrics and Gynecology, Clinical Research Development Unit, Kosar Hospital, Qazvin University of Medical Sciences, Qazvin, Iran Sonia Oveisi Department of Pediatrics, Metabolic Diseases Research Center, Qazvin University of Medical Sciences, Qazvin, Iran Maryam Rafiei Department of Obstetrics and Gynecology, Clinical Research Development Unit, Kosar Hospital, Qazvin University of Medical Sciences, Qazvin, Iran Leila Amini Department of Obstetrics and Gynecology, Clinical Research Development Unit, Kosar Hospital, Qazvin University of Medical Sciences, Qazvin, Iran 2021 04 07 2021 09 01 Objective: Placenta Accreta Spectrum (PAS) affects approximately one in a thousand deliveries. Very few studies evaluated PAS risk factors based on their location. In this study, we have investigated the effects of placenta location on placental adhesion-related complications, its risk factors, and outcomes. Materials and methods: We performed a retrospective cohort study of pathology-confirmed cases of PAS from patients with peripartum hysterectomy, at a large educational hospital in Qazvin, Iran, from 2009 to 2019. Placenta location was found by ultrasound reports and intraoperative evaluation. We measured demographic features, basic characteristics, maternal and neonatal outcomes based on placental location including anterior, posterior, and lateral in Placenta Accreta Spectrum. Chi-square, t-test, and one-way ANOVA were used to examine the relation of complications, risk factors, and outcomes in PAS. Results: A review of 70 cases showed the distribution of placenta location as follows: 57% anterior, 27% posterior, and 16% lateral. The mean gestational age at delivery was 35 (33-39) weeks. In 78.6% (n=55) of the patients, an association with placenta previa and in 94/2% (n=66) of cases a history of cesarean section was found, however, it was not significantly correlated with placenta location (p=0.082). We found that surgery duration was significantly longer in patients with lateral PAS (155±38, vs 129.35±33.8 and 133.15±31.5 for anterior and posterior placenta respectively, p=0.09). Patients with lateral PAS also bled more than the remaining two groups (2836 ml for lateral PAS vs 2002 and 1847 for anterior and posterior placenta respectively, p=0.022). Moreover, women with a history of uterine surgery were more likely to have posterior PAS compared to those with anterior and lateral PAS (p=0.035). Conclusion: Differences in complications, risk factors, and outcomes of PAS based on placenta location may lead to improved diagnosis and decreased morbidity in women. https://jfrh.tums.ac.ir/index.php/jfrh/article/view/1751 https://jfrh.tums.ac.ir/index.php/jfrh/article/download/1751/578

Tehran University of Medical Sciences Journal of Family and Reproductive Health 1735-8949 15 4 2021 11 28 266 270 Ganbayar Batmunkh Division of Medical Genetics, National Center of Maternal and Child Health, Ulaanbaatar, Mongolia Purevtogtokh Myagmartseren Infertility clinic, National Center of Maternal and Child Health, Ulaanbaatar, Mongolia Tuul Bayarsaikhan Division of Medical Genetics, National Center of Maternal and Child Health, Ulaanbaatar, Mongolia Tserendagva Dalkh International School of Mongolian Medicine, Mongolian National University of Medical Sciences, Ulaanbaatar, Mongolia Munkhtuya Tumurkhuu Department of Chemistry, North Carolina State University, North Carolina, USA 2021 02 17 2021 08 17 Objective: This study aimed to investigate the cause of primary infertility in a rare case with unilateral absence of vas deferens. Case report: A 35-year-old man was presented to the Infertility Clinic at the National Center of Maternal and Child Health (NCMCH) with an eight-year history of primary infertility. Clinical examination showed a normal intelligence with a coarse facial appearance and small testicles. Hormonal tests detected elevated levels of prolactin (PRL), follicle stimulating hormone (FSH), and luteinizing hormone (LH), and low levels of testosterone. Chromosomal analysis with fluorescence in situ hybridization (FISH) revealed a 46XX with SRY (sex-determining region Y) positive karyotype with translocation of the SRY gene (46XX der(X)t(X:Y)(p11.1:p11.3)(SRY+)). Magnetic resonance imaging (MRI) revealed bilateral seminal vesicles atrophy and agenesis of the vas deferens on the right side, which is rarely found in 46, XX male syndrome. Conclusion: Although 46XX testicular disorder of sexual development (DSD) cases are rare, multiple aspects of the clinical examinations are important to make an accurate diagnosis and to provide proper genetic counseling and guidance to patients in their long-term management https://jfrh.tums.ac.ir/index.php/jfrh/article/view/1701 https://jfrh.tums.ac.ir/index.php/jfrh/article/download/1701/584

Tehran University of Medical Sciences Journal of Family and Reproductive Health 1735-8949 15 4 2021 11 28 236 241 Sara Peña-Lizola Center for Reproductive Medicine, Department of Gynecology and Obstetrics, Dr. José Eleuterio Gonzalez University Hospital, Autonomous University of Nuevo Leon, Monterrey, Mexico Luis Sordia-Hernandez Center for Reproductive Medicine, Department of Gynecology and Obstetrics, Dr. José Eleuterio Gonzalez University Hospital, Autonomous University of Nuevo Leon, Monterrey, Mexico Selene Garcia-Luna Center for Reproductive Medicine, Department of Gynecology and Obstetrics, Dr. José Eleuterio Gonzalez University Hospital, Autonomous University of Nuevo Leon, Monterrey, Mexico Otto Valdes-Martinez Center for Reproductive Medicine, Department of Gynecology and Obstetrics, Dr. José Eleuterio Gonzalez University Hospital, Autonomous University of Nuevo Leon, Monterrey, Mexico Cassandra Skinner-Taylor Rheumatology and Immunology Service, Dr. Jose Eleuterio Gonzalez University Hospital, Autonomous University of Nuevo Leon, Monterrey, Mexico Mario Garza-Elizondo Rheumatology and Immunology Service, Dr. Jose Eleuterio Gonzalez University Hospital, Autonomous University of Nuevo Leon, Monterrey, Mexico OScar Vidal-Gutierrez Center for Reproductive Medicine, Department of Gynecology and Obstetrics, Dr. José Eleuterio Gonzalez University Hospital, Autonomous University of Nuevo Leon, Monterrey, Mexico Jesus Villarreal-Perez Department of Endocrinology, Dr. Jose Eleuterio González University Hospital, Autonomous University of Nuevo Leon. Monterrey, Mexico Miryam Eguia-Bernal Rheumatology and Immunology Service, Dr. Jose Eleuterio Gonzalez University Hospital, Autonomous University of Nuevo Leon, Monterrey, Mexico Felipe Morales-Martinez Center for Reproductive Medicine, Department of Gynecology and Obstetrics, Dr. José Eleuterio Gonzalez University Hospital, Autonomous University of Nuevo Leon, Monterrey, Mexico 2021 04 08 2021 08 22 Objective: Subfertility is commonly observed in patients with rheumatoid arthritis (RA). Although the causes are not well established, the alteration of the ovarian reserve is thought to contribute to the lower chances of pregnancy. This cross-sectional study aimed to evaluate the ovarian reserve in patients with RA. Materials and methods: Two parameters associated with ovarian reserves such as the antral follicle count (AFC) and the anti-müllerian hormone (AMH) were assessed in 38 patients with RA. We also analyzed the correlation of these parameters with the medication used to treat this pathology and with the illness severity. Results: The AMH levels in women with RA were comparable to those found on healthy individuals although the RA patients were more likely to have a low AFC. Ovarian reserve and RA were neither influenced by parameters of disease activity nor by the use of medication. Conclusion: The ovarian reserve in women with RA was similar to that found in healthy individuals. https://jfrh.tums.ac.ir/index.php/jfrh/article/view/1752 https://jfrh.tums.ac.ir/index.php/jfrh/article/download/1752/579

Tehran University of Medical Sciences Journal of Family and Reproductive Health 1735-8949 15 4 2021 11 28 271 274 Maryam Abiri Department of Medical Genetics, Faculty of Medicine, Iran University of Medical Sciences, Tehran, Iran AND Shahid Akbarabadi Clinical Research Development Unit, Iran University of Medical Sciences, Tehran, Iran Maryam Hassanlou Faculty of Biology, Women’s University of Semnan (Farzanegan), Semnan, Iran uthor> Azadeh Tarafdari Menshadi Vali-E-Asr Reproductive Health Research Center, Family Health Research Institute, Tehran University of Medical Sciences, Tehran, Iran Mamak Shariat Maternal, Fetal & Neonatal Research Center, Family Health Research Institute, Tehran University of Medical Sciences, Tehran, Iran Saiedeh Shahsavari Department of Obstetrics and Gynecology, Hormozgan University of Medical Sciences, Bandar Abbas, Iran Fedyeh Haghollahi Vali-E-Asr Reproductive Health Research Center, Family Health Research Institute, Tehran University of Medical Sciences, Tehran, Iran Elham Azimi Nekoo Jacobi Medical Center / Albert Einstein University, New York, United States 2023 06 13 2023 08 15 Objective: Platelet Rich Plasma (PRP) is proposed to have important role in cell division and proliferation, angiogenesis and health. This study evaluates the effect of a single injection of autologous PRP on ovarian response markers in women with poor ovarian response (POR). Materials and methods: This non-randomized clinical trial was conducted between August 2020 and September 2021. Fifty six women with Bologna criteria for POR willingly chose to participate in one of the following groups: PRP for one cycle in the time of oocyte pickup (OPU) (intervention group, n= 34) or control group (n=22).The primary outcomes were: number and quality of oocytes in coming 2 cycles of ICSI, and Anti Mullerian Hormone (AMH) level two months after PRP injection. The secondary outcomes were the number and quality of embryos and chemical pregnancy rate after embryo transfer. Results: A total of 45 participants continued the study, of which 23 were in the intervention group and 22 in control group. There were no demographic differences between two groups. At a two cycle follow up, PRP group experienced a significant improvement in AMH level and there was no respective change in control group. In one year follow up the overall pregnancy rates were same in both groups (3% Vs. 0, p=.60), while there was no difference in cumulative number and quality of embryos. Conclusion: PRP injection can improve ovarian reserve marker without adverse effects. Further evidence is required to evaluate the impact of PRP on assisted reproduction outcomes. https://jfrh.tums.ac.ir/index.php/jfrh/article/view/2400 https://jfrh.tums.ac.ir/index.php/jfrh/article/download/2400/652

Tehran University of Medical Sciences Journal of Family and Reproductive Health 1735-8949 17 3 2023 09 03 174 178 Fateme Salehi Department of Obstetrics and Gynecology, Yas Hospital, Tehran University of Medical Sciences, Tehran, Iran Sara Saeedi Department of Obstetrics and Gynecology, Yas Hospital, Tehran University of Medical Sciences, Tehran, Iran Zeynab Amiriariya Department of Obstetrics and Gynecology, Yas Hospital, Tehran University of Medical Sciences, Tehran, Iran Elham Feizabad Department of Obstetrics and Gynecology, Yas Hospital, Tehran University of Medical Sciences, Tehran, Iran 2023 06 21 2023 08 15 Objective: Pelvic access is a challenging matter in abdominal hysterectomy especially in obese patients and presence of pelvic adhesions. Uterus manipulators (UM) have been used in a number of studies on laparoscopic approach to improve surgical performance. This study aimed to assess the impact of UM application on the operation time and blood loss in total abdominal hysterectomy (TAH) for benign diseases. Materials and methods: Forty-one patients aged 34 to 56 years were enrolled for abdominal hysterectomy – 20 as the case group (hysterectomy with UM application) and 21 as the control group (conventional hysterectomy). In the case group, UM was used after uterus artery ligation during TAH. The control group underwent traditional TAH. Results: The mean operation time was significantly less in TAH with UM compared to traditional TAH (90.23 ± 10.54 minutes vs. 140.5 ± 16.61 minutes; p-value<0.001). The mean decline between preoperative and 12-hour postoperative hemoglobin was 0.74 ± 0.23 mg/dL in the TAH with UM group and 1.65± 1.02 mg/dL in the traditional TAH group (p-value<0.001). Also, no difference was detected in intra- and post-operative complications. Conclusion: The current study showed that, using UM is beneficial in total abdominal hysterectomy by decreasing the operative time and blood loss. https://jfrh.tums.ac.ir/index.php/jfrh/article/view/2412 https://jfrh.tums.ac.ir/index.php/jfrh/article/download/2412/653

Tehran University of Medical Sciences Journal of Family and Reproductive Health 1735-8949 17 3 2023 09 03 179 184 Azadeh Shabani Preventative Gynecology Research Center (PGRC), Department of Obstetrics and gynecology, Shahid Beheshti University of Medical Sciences, Tehran, Iran Mahshid Farahbakhsh School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran Azadeh Mazaheri Meybodi Hospital Research Development Committee and Department of Psychiatry, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran Nafiseh Faghih Gynecology Department, Taleghani Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran Mohammad Haddadi Vali-E-Asr Reproductive Health Research Center, Family Health Research Institute, Tehran University of Medical Sciences, Tehran, Iran 2023 07 26 2023 08 16 Objective: Postpartum depression (PPD) is a common mental disorder among women and it can cause negative consequences for them, children, and families; however, accurate statistics and underlying factors on PPD and its severity are not available in Iran. Materials and methods: In this cross-sectional study, 200 women referred to an academic hospital for normal vaginal delivery, which had a full-term and single pregnancy and had passed between 6 weeks and 6 months of delivery, were selected by convenience sampling methods. The Edinburgh Depression Inventory and the checklist for demographic information of mothers were completed. Results: The prevalence of postpartum depression was 11.0% and 68.2% of mothers had a mild type. 31.8% had a history of depression. There was a significant relationship between the severity of postpartum depression in women with a previous history of depression (P = 0.012). Between postpartum depression and maternal age (P = 0.115), body mass index at delivery (P = 0.571), number of pregnancies (P = 0.693), number of deliveries (P = 0.446), number of abortions (P = 0.424), willing or unwilling pregnancy (P = 0.451), neonatal sex (P = 0.533), history of neonatal hospitalization (P = 0.725), previous history disease (P = 0.725) was no statistical association. Conclusion: The prevalence of PPD was approximately 11%, and there was a significant association between postpartum depression severity and a history of depression Physicians and policymakers should consider early screening for PPD, especially among women with previous depression. https://jfrh.tums.ac.ir/index.php/jfrh/article/view/2438 https://jfrh.tums.ac.ir/index.php/jfrh/article/download/2438/654

Tehran University of Medical Sciences Journal of Family and Reproductive Health 1735-8949 17 3 2023 09 03 185 190 Iraj Shahramian Department of Pediatrics, Zabol University of Medical Sciences, Zabol, Iran Leli Rezaie Kahkhaie Department of Internal Medicine, School of Medicine, Amiralmomenin Hospital, Zabol University of Medical Sciences, Zabol, Iran Khadije Rezaie Keikhaie Department of Obstetrics and Gynecology, School of Medicine, Medicinal Plants Research Center, Zabol University of Medical Sciences, Zabol, Iran Mahdi Shirdel Kahkha Zhaleh Student Research Committee, Zabol University of Medical Sciences, Zabol, Iran Mahdi Afshari Pediatric Gastroenterology and Hepatology Research Center, Zabol University of Medical Sciences, Zabol, Iran 2023 07 16 2023 08 16 Erratum. J Family Reprod Health. 2023;17(4):270.DOI: https://doi.org/10.18502/jfrh.v17i4.14667 Objective: Changes in endocrine, nervous, renal, cardiovascular, and respiratory systems during pregnancy have been studied, but changes in liver function have been poorly studied. Therefore, the purpose of this study was to investigate the trend of changes in liver enzymes in normal pregnancy. Materials and methods: This prospective longitudinal study included 68 pregnant women who were referred to the Obstetrics and Gynecology Clinic of Amiral Momenin Hospital in Zabol in 2021. In terms of the trimester of pregnancy, the presence of underlying diseases, history of previous pregnancies, disorders of the enzymes of recent patients, the patients were evaluated, and the information from the patients' files was analyzed. Results: The average AST levels in pregnant women in the first, second, and third trimesters were 16.82, 17.47, and 18.00, respectively, which show that garlic consumption is increasing. The average PT in pregnant women decreased in the first, second, and third trimesters. The average direct and total bilirubin levels in pregnant women in the first and second trimesters showed a constant trend. The amount of total protein increased in pregnant women during the first, second, and third trimesters. In the second and third trimesters, the enzyme level was significantly higher in pregnant women than in nonpregnant women. The level of GGT in pregnant women in the first, second, and third trimesters showed a different trend. Conclusion: Accurate evaluation of patients, especially in the third trimester, is necessary from the point of view of increasing enzyme levels in other countries.   https://jfrh.tums.ac.ir/index.php/jfrh/article/view/2424 https://jfrh.tums.ac.ir/index.php/jfrh/article/download/2424/655

Tehran University of Medical Sciences Journal of Family and Reproductive Health 1735-8949 17 3 2023 09 03 191 193 Paola Algeri