Tehran University of Medical Sciences Journal of Family and Reproductive Health 1735-8949 11 4 2017 12 10 179 184 EN Vasilios Pergialiotis Laboratory of Experimental Surgery and Surgical Research, Medical School, National and Kapodistrian University of Athens, Athens, Greece Diamanto Koutaki Laboratory of Experimental Surgery and Surgical Research, Medical School, National and Kapodistrian University of Athens, Athens, Greece Evangelos Christopoulos-Timogiannakis Laboratory of Experimental Surgery and Surgical Research, Medical School, National and Kapodistrian University of Athens, Athens, Greece Paraskevi Kotrogianni Laboratory of Experimental Surgery and Surgical Research, Medical School, National and Kapodistrian University of Athens, Athens, Greece Despina N. Perrea Laboratory of Experimental Surgery and Surgical Research, Medical School, National and Kapodistrian University of Athens, Athens, Greece Georgios Daskalakis Department of Obstetrics &Gynecology, National and Kapodistrian University of Athens, Alexandra Hospital, Athens, Greece 2017 10 16 2017 12 24 Objective: Serum Anti-Müllerian hormone (AMH) has been implicated in the pathogenesis of cardiovascular disease. Its prognostic value in determining the risk of developing preeclampsia remains, to date, unclear. The purpose of the present systematic review is to accumulate current evidence in this field. Materials and methods: We searched Medline (1966–2017), Scopus (2004–2017), Clinicaltrials.gov (2008–2017), EMBASE (1980-2017), LILACS (1986-2017) and Cochrane Central Register of Controlled Trials CENTRAL (1999-2017) databases. Results: Four studies were included in with a total number of 401 women. Among them 146 had preeclampsia while 232 were recruited as normotensive controls. Current data are suggestive of the potential predictive value of serum AMH as its levels seem to be lower among women that develop preeclampsia. One study reported that women with and AMH value below the 10th percentile of the studied population had a 3.3 increased risk of developing preeclampsia (OR 3.3, 95% CI 1.2–8.7, p = 0.01). Conclusion: Taking in mind these findings, future studies are needed in this field to establish optimal cut-off values and evaluate the specificity and sensitivity of this biomarker during the first trimester of pregnancy. https://jfrh.tums.ac.ir/index.php/jfrh/article/view/710 https://jfrh.tums.ac.ir/index.php/jfrh/article/download/710/398

Tehran University of Medical Sciences Journal of Family and Reproductive Health 1735-8949 11 4 2017 12 10 185 190 EN Parvin Abedi Department of Midwifery, Reproductive Health Promotion Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran Hoda Rastegar Department of Midwifery, Reproductive Health Promotion Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran Mahboobeh Valiani Department of Midwifery, Nursing and Midwifery Care Research Center, School of Nursing and Midwifery, Isfahan University of Medical Sciences, Isfahan, Iran Najimeh saadati Department of Obstetrics & Gynecology, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran; Fellowship Perinatology Ward, Maternal-Fetal Medicine Research Center, Shiraz University of Medical Sciences, Shiraz, Iran 2017 09 05 2017 12 03 Objective: This study aimed to evaluate the effect of auriculotherapy on labor pain, the length of the active phase, and episiotomy rate among reproductive aged Iranian women. Materials and methods: In this study, 80 women were assigned to two groups: auriculotherapy (n = 40) and control group (n = 40). Auriculotherapy was performed in the earlobe in the Zero, Shen Men, Uterus, Pelvic, Abdomen, Spleen, External genitalia, and Master cerebral regions in the cervix dilation of 4, 6, and 8 cm between uterine contractions. The control group received routine hospital care. The labor pain, duration of the active phase, and rate of episiotomy were assessed in two groups. The independent t- test and chi-square were used for statistical purposes. Results: The mean of labor pain during the active phase was 7.56 ± 0.83 in the auriculotherapy group and 8.43 ± 0.69 in the control group (p < 0.001). The length of active phase was significantly lower in the auriculotherapy than that in the control group (176.2 ± 1 min vs. 342.8±87.2 min, p < 0.001). The rate of normal vaginal delivery (without an episiotomy or perineal tears) was significantly higher in the auriculotherapy group than that in the control group (50% vs. 2.5%, p < 0.001). Conclusion: Auriculotherapy is safe, cost effective and devoid of side effects to reduce the labour pain, length of the active phase and the rate of episiotomy in nulliparous women. This method can be considered as a complementary medicine in labour. https://jfrh.tums.ac.ir/index.php/jfrh/article/view/674 https://jfrh.tums.ac.ir/index.php/jfrh/article/download/674/399

Tehran University of Medical Sciences Journal of Family and Reproductive Health 1735-8949 11 4 2017 12 10 225 227 EN Savita Singhal Department of Obstetrics and Gynecology, PGIMS, Rohtak, India Susheela Chaudhary Department of Obstetrics and Gynecology, PGIMS, Rohtak, India Kriti Agarwal Department of Obstetrics and Gynecology, PGIMS, Rohtak, India Anjali Gupta Department of Obstetrics and Gynecology, PGIMS, Rohtak, India 2017 06 18 2017 11 12 Objective: To report a case of Successful Pregnancy Outcome in Recurrent Ovarian Cancer in a 26 year Old. Case Report: A 26 years old primigravida presented in antenatal clinic at 23 weeks of pregnancy with recurrence of ovarian cancer of mucinous type. Following refusal of surgical management, two courses of single dose carboplatin was administered. However, before third cycle of chemotherapy could be administered ,there was deranged liver functions tests, following which elective Cesarean section with staging laparotomy was planned at 34 weeks for breech presentation with oligohydramnios. A live healthy baby girl 2.3kg was delivered. Total abdominal hysterectomy with right salpingo-oopherectomy, infracolic omentectomy, appendectomy was done. The final diagnosis was recurrent mucinous ovarian adenocarcinoma. Postoperatively, she was given six cycles of chemotherapy (carboplatin and paclitaxel). Conclusion: Chemotherapy and surgery, both are safe beyond first trimester and multidisciplinary treatment must be planned after taking into account the wishes of couple. https://jfrh.tums.ac.ir/index.php/jfrh/article/view/635 https://jfrh.tums.ac.ir/index.php/jfrh/article/download/635/405

Tehran University of Medical Sciences Journal of Family and Reproductive Health 1735-8949 11 4 2017 12 10 191 196 EN Tahereh Behroozi-Lak Reproductive Health Research Center,Department of Obstetrics and Gynecology, Faculty of Medicine, Urmia University of Medical Sciences, Urmia, Iran Ameneh Akbary Reproductive Health Research CenterDepartment of Obstetrics and Gynecology, Faculty ofMedicine, Urmia University of Medical Sciences, Urmia, Iran Shabnam Vazifekhah Reproductive Health Research Center, Department of Obstetrics and Gynecology, Faculty of Medicine, Urmia University of Medical Sciences, Urmia, Iran Mohammad Naghavi-Behzad Students’ Research Committee, Tabriz University of Medical Sciences, Tabriz, Iran Mohammad Mirza-Aghazadeh-Attari Medical Philosophy and History Research Center, Tabriz University of Medical Sciences, Tabriz, Iran 2017 09 13 2018 01 14 Objective: Preterm delivery is a common and eventful phenomenon with long standing complications, heavily burdening the health system. Many risk factors have been suggested to increase the likelihood of this event, one being hypothyroidism and high levels of anti-thyroid antibodies. The present study sought to explore the association between hypothyroidism and anti-thyroid antibodies with preterm delivery. Materials and methods: A case control study was conducted on 400 patients attending Educational-Medical centers of Urmia University of Medical Sciences (Urmia, Iran) between November 2013 and April 2016, in which 200 patients with term deliveries and 200 patients with preterm deliveries were compared for differences in hypothyroidism, existence of anti- thyroperoxidase (TPO) antibodies based on blood samples obtained from the patients which were tested using chemi-luminescence method. Results: In the group of patients with preterm delivery, 85 patients had hypothyroidism (42.5%), and from the term delivery group, 67 patients (33.5%) had hypothyroidism, the difference was not statistically significant (p = 0.14). But, when groups of early and late preterm deliveries were compared in terms of having anti-TPO antibodies, there was a significant difference between them, with early preterm delivery having 8 patients positive out of 44 patients and late preterm delivery having 7 positives out of 141 patients (p = 0.004). Conclusion: Hypothyroidism had an insignificant effect on preterm delivery rates, but the existence of anti–TPO antibodies in the serum had a significant increasing effect on early preterm deliveries and could be regarded as a risk factor. https://jfrh.tums.ac.ir/index.php/jfrh/article/view/681 https://jfrh.tums.ac.ir/index.php/jfrh/article/download/681/400

Tehran University of Medical Sciences Journal of Family and Reproductive Health 1735-8949 11 4 2017 12 10 197 201 EN Masoumeh Asgarshirazi Pediatrics Department, Tehran University of Medical Sciences, Tehran, Iran Monir Farokhzade Soltani Maternal, Fetal & Neonatal Research Center, Tehran University of Medical Sciences, Tehran, Iran Zarrintaj Keihanidost Pediatrics Department, Tehran University of Medical Sciences, Tehran, Iran Mamak Shariat Maternal, Fetal & Neonatal Research Center, Tehran University of Medical Sciences, Tehran, Iran 2017 09 24 2018 02 04 Objective: This cross sectional study aims to survey developing feeding disorders and nutritional deficiencies disorders in children with neurodevelopmental disorders such as cerebral palsy. Materials and methods: A total of 50 children (28 boys and 22 girls) with cerebral palsy and symptoms suggesting gastrointestinal problems such as choking, recurrent pneumonia and poor weight gain, who referred to the Pediatric department of Vali-asr Hospital, Imam Khomeini hospital complex between 1 October 2012 and 30 October 2013, were checked. Motor function classification system was used to classify patient's functional gross motor severity. All patients were examined and underwent deglutition videofluroscopy (modified barium swallow) and upper GI endoscopy with esophageal biopsies. Outcome of this study was the prevalence of oropharyngeal incoordination and GERD. Its relationship with some variables like motor and cognitive developmental delay were analyzed and p value < 0.05 was considered significant. Medical therapy and/or oral physiotherapy and nutritional rehabilitation were started. They were examined after 6 months of treatment. Decrease in choking and episodes of respiratory infections that needed hospitalization and weight gain after 6 months treatment were considered as secondary outcomes (response to treatment). Results: Prevalence of GERD was 66% and oropharyngeal dysphagia was estimated 82%. According to results of video-fluroscopy and endoscopic biopsies, 52% of patients were affected by both GERD and oropharyngeal dysfunction. The gross motor function disability was the only variable that significantly related to the prevalence of feeding disorders (p = 0.015). Despite nutritional rehabilitation only 46% of children have weight gain. Conclusion: Feeding disorders such as GERD and oropharyngeal dysfunction are more prevalent in children with cerebral palsy especially in children with severe gross motor disabilities. Since, clinical manifestations of these disorders can be similar accurate diagnostic methods should be selected for all children with cerebral palsy and gastrointestinal symptoms. Treatment should start early to reduce the complications and improve outcomes. https://jfrh.tums.ac.ir/index.php/jfrh/article/view/689 https://jfrh.tums.ac.ir/index.php/jfrh/article/download/689/401

Tehran University of Medical Sciences Journal of Family and Reproductive Health 1735-8949 11 4 2017 12 10 202 210 EN Davoud Pourmarzi Reproductive Health Research Center, Guilan University of Medical Sciences, Rasht, Iran Ashraf Khoramirad Faculty of Nursing and Midwifery, Qom University of Medical Sciences, Qom, Iran Mina Gaeeni Faculty of Nursing and Midwifery, Qom University of Medical Sciences, Qom, Iran 2017 11 06 2018 01 23 Objective: This study aimed to report on perceived stigma by PLWH and factors that affect it. Materials and methods: A cross-sectional study was carried out on 120 PLWH in Qom, Iran from November 2015 to April 2016. Persian version of Fife and Wright's scale was used to measure perceived stigma. Results: The mean score of stigma was 73.19 ± 12.23 (range: 48-97). The means of external stigma and internal stigma were 43.70 ± 8.61 (range: 19-60), and 29.49 ± 5.32 (range: 17-40), respectively. Living in a rural areas (β = 10.341, p = 0.006), unemployment status (β = 6.910, p = 0.006), and poor support from family members (β = 4.772, p = 0.028) significantly increased the level of perceived stigma. PLWH experience a considerable level of stigma in their daily life. Mass media involvement to increase public awareness and reduce HIV related stigma need be more highlighted. Conclusion: Working with the patients' families, interventions in the rural areas and workplaces, and providing social supports is necessary to minimize the HIV related stigma. https://jfrh.tums.ac.ir/index.php/jfrh/article/view/725 https://jfrh.tums.ac.ir/index.php/jfrh/article/download/725/402

Tehran University of Medical Sciences Journal of Family and Reproductive Health 1735-8949 11 4 2017 12 10 211 218 EN Sakineh Dadipoor Mother and Child Welfare Research Center, School of Public Health, Hormozgan University of Medical Sciences, Bandar Abbas, Iran Ali Ramezankhani Department of Public Health, School of Public Health, Shahid Beheshti University of Medical Sciences, Tehran, Iran Azin Alavi Fertility and Infertility Research Center, Faculty of Medicine, Hormozgan University of Medical Sciences, Bandar Abbas, Iran Teamur Aghamolaei Mohammad Hosein Haghighizadeh Department Biostatistics, School of Health, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran Mina Iravani Reproductive Health Promotion Research Center, Department of Midwifery, School of Nursing and Midwifery, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran 2022 12 24 2023 05 28 Objective: Fetal occiput posterior (OP) position is associated with more maternal and neonatal complications. This study aimed to investigate the effect of maternal position during labor on fetal OP position and pregnancy outcomes. Materials and methods: This randomized clinical trial study included 180 primigravida women in labor with a single fetus and approved OP position. Participants were randomly allocated into three groups: semi-prone position (n=45), knee-chest position (n=45), and supine position (n=90). All participants were placed in the defined positions 15-30 min in labor until delivery. Data collected using Visual Analogue Scale and researcher made checklist. The ANOVA, Tukey post hoc, and the chi-square test were used to analyze. Results: Among all participants who had OP, after intervention 16.3% in the semi-prone position, 14/3 % in the knee-chest position, and 33.7% of the control groups remained with OP at birth (X3=7/87, P=0.019). The rate of natural delivery was significantly higher in the semi-prone position and knee-chest position. The duration of active phase of labor and low back pain were significantly reduced in the semi-prone and knee-chest position compared to the control groups (P<0.05). There were no differences in the duration of the third stage of labor, APGAR score, and the rate of neonatal addition to neonatal intensive care unit, using oxytocin, and perineal tears (P>0.05). Conclusion: The semi-prone and knee-chest positions increase the spontaneous rotation of occiput to the anterior position, vaginal delivery rates as well as a reduction in duration of active phase of labor and low back pain after delivery. https://jfrh.tums.ac.ir/index.php/jfrh/article/view/2248 https://jfrh.tums.ac.ir/index.php/jfrh/article/download/2248/640

Tehran University of Medical Sciences Journal of Family and Reproductive Health 1735-8949 17 2 2023 06 11 93 99 Rayhan Islam School of Health & Life Sciences, North South University, Dhaka, Bangladesh Khandakar Shafiur Rahaman RANAS Ltd. – Spin-off of Eawag, Zurich, Switzerland AND London School of Hygiene and Tropical Medicine, London, UK Mohammad Hawlader Department of Public Health, North South University, Dhaka, Bangladesh 2023 01 03 2023 05 28 Objective: Erectile dysfunction (ED) is a common cause of sexual disorders in men with limited treatment options. This study aimed to determine the efficacy of low-intensity extra corporal shockwave therapy (LI-ESWT) in patients suffering from ED. Materials and methods: A single-group, pre-test, and post-test pre-experimental study were conducted. Thirty-one ED patients were prospectively selected according to the eligibility criteria. In each session, 3000 shocks were applied at 5 points over the penis. Eight sessions were delivered in total with a 2–3-day interval. The patient’s condition was assessed using the International Index of Electric Function (IIEF-5) questionnaire at baseline and one month after the last treatment session. Paired t-test was used to determine the difference between the pre-test and post-test. Results: Mean age of the patients was 44.6 (± 14.70) ranging from 25 to 78 years. The majority of them were married (83.9%) and service providers (51.6%). We have also found 51.6% overweight