Tehran University of Medical Sciences Journal of Family and Reproductive Health 1735-8949 19 4 2025 12 31 310 317 Mahla Abidi Central Tehran Branch, Islamic Azad University, Tehran, Iran Mansooreh Fazilati Department of Psychology, Central Tehran Branch, Islamic Azad University, Tehran, Iran Farshad Samadi Imam Ali (AS) Hospital, North Khorasan University of Medical Sciences, Bojnurd, Iran 2025 11 02 2025 11 30 Objective: The present study aimed to predict sleep disorders based on psychological distress and emotional dysregulation among adolescent girls. Materials and methods: This research employed a descriptive-correlational design. The statistical population included all adolescent girls studying in secondary high schools in Tehran during the first semester of the 2024–2025 academic years, totaling 87,222 students. A sample size of 300 participants was determined and selected using a multistage cluster random sampling method. Data were collected using the Sleep Disorders Questionnaire, the Psychological Distress Scale and the Emotional Dysregulation Questionnaire. Statistical analyses were performed using SPSS version 27. Results: The results showed that 45.3% of the variance in sleep disorders was predicted by psychological distress and emotional dysregulation. There was a positive and significant relationship between psychological distress and sleep disorders (β = 0.645). Moreover, emotional dysregulation was positively and significantly related to sleep disorders (β = 0.576). Additionally, stress (β = 0.669), anxiety (β = 0.630), and depression (β = 0.450) showed positive and significant associations with sleep disorders. Conclusion: Based on the findings, psychological distress and emotional dysregulation play significant roles in predicting sleep disorders and explain a considerable proportion of their variance. Therefore, interventions targeting these psychological variables may help improve sleep quality and enhance mental health among individuals. https://jfrh.tums.ac.ir/index.php/jfrh/article/view/3556 https://jfrh.tums.ac.ir/index.php/jfrh/article/download/3556/745