Tehran University of Medical Sciences Journal of Family and Reproductive Health 1735-8949 18 1 2024 05 07 36 43 Soudabeh Ershadi Manesh Department of Psychology, North Tehran Branch, Islamic Azad University, Tehran, Iran Mohammad Javad Bagian Kulemarzi Department of Psychology, University of Razi Kermanshah, Kermanshah, Iran 2024 02 21 2024 03 12 Objective: This study aimed to predict suicide attempts based on behavioral activation and inhibition systems (BAS/BIS) with the mediating role of cognitive emotion regulation (CER) strategies among adolescents of Abyek City. Materials and methods: The research methodology was descriptive-correlational. The cluster sampling method was used, and the resulting sample included 194 adolescents who responded to the BAS/BIS questionnaire (Carver & White, 1994), CER questionnaire, and Beck scale for suicide ideation. Path analysis was employed to evaluate the proposed model using AMOS 24.0 and SPSS 27 softwares. Results: The findings indicate that the proposed model is fitted with the data well. The results of path analysis showed that the BAS/BIS systems explain 27% of the variance of maladaptive CER and 61% of the variance of adaptive CER. In addition, maladaptive CER, BAS, and BIS explain 65% of the variance of suicide attempts. Conclusion: Low levels of BAS, high levels of BIS, and the use of maladaptive CER skills can be considered risk factors for suicide attempts in adolescents.   https://jfrh.tums.ac.ir/index.php/jfrh/article/view/2639 https://jfrh.tums.ac.ir/index.php/jfrh/article/download/2639/672