Tehran University of Medical Sciences Journal of Family and Reproductive Health 1735-8949 17 2 2023 06 11 113 115 Carolina Quental USF Prelada Daniel Brito Family Health Unit, Espaço Saúde, Porto, Portugal João Sobral Family Health Unit, Baltar, Paredes, Portugal Ana Mafalda Macedo Family Health Unit, Prelada, Porto, Portugal 2023 01 31 2023 05 28 Objective: In Raynaud's phenomenon of the nipple there is a change in color, accompanied by pain or discomfort during breastfeeding. Case report: A 29-years old female patient, breastfeeding, develops a severe bilateral nipple pain during and after breastfeeding and biphasic change in nipple color, with difficulties in the breastfeeding technique. She was medicated with nifedipine and recommended application of warm compresses to the nipples and use of electric breast pump, showing complete resolution after four weeks of treatment. Conclusion: Raynaud's phenomenon of the nipple should be considered in breastfeeding women who report nipple pain or discomfort. In clinical practice, nipple pain is a very frequent complaint, and responsible for many cases of early abandonment of breastfeeding. It is therefore essential to make an early diagnosis and implement a correct and immediate treatment. https://jfrh.tums.ac.ir/index.php/jfrh/article/view/2278 https://jfrh.tums.ac.ir/index.php/jfrh/article/download/2278/645