Tehran University of Medical Sciences Journal of Family and Reproductive Health 1735-8949 17 2 2023 06 11 109 112 Elias Mansour Department of Urology, University of Balamand, El-Koura‎, ‎Lebanon Samer Danaf Department of Urology, University of Balamand, El-Koura‎, ‎Lebanon Daniel Ghoussainy Department of Urology, University of Balamand, El-Koura‎, ‎Lebanon Georges Assaf Department of urology, Saint George hospital university medical center, Achrafieh, Lebanon Imad Ghantous Department of urology, Saint George hospital university medical center, Achrafieh, Lebanon Fouad El-Khoury Department of urology, Saint George hospital university medical center, Achrafieh, Lebanon 2022 11 27 2023 05 28 Objective: Present a case of zuclopenthixol associated priapism, literature review and focus on the stuttering priapism entity as a potential serious complication as well as providing information about possible preventive treatments. Case report: A 44 year-old male patient with history of cocaine abuse with associated priapism presents with acute painful erection after starting zuclopenthixol for treatment of a psychotic episode. This episode was later followed by many other similar episodes defined as stuttering priapism. Conclusion: Acute ischemic priapism is a potential serious side effect of antipsychotics that physicians especially psychiatrists needs to be aware of especially if the patient has previous episodes in order to prevent reoccurrence. https://jfrh.tums.ac.ir/index.php/jfrh/article/view/2227 https://jfrh.tums.ac.ir/index.php/jfrh/article/download/2227/644