Tehran University of Medical Sciences Journal of Family and Reproductive Health 1735-8949 16 2 2022 05 24 155 160 EN Ruchi Nagpal Department of Pathology, Bhaskar Medical College and General Hospital, Hyderabad, Telangana, India Hari Vanam Department of Microbiology, Bhaskar Medical College and General Hospital, Hyderabad, Telangana, India Harshi Dhingra Department of Pathology, Adesh Institute of Medical Sciences and Research, Bathinda, Punjab, India Ravali Banswada Department of Obstetrics and Gynaecology, Bhaskar Medical College and General Hospital, Hyderabad, Telangana, India 2021 11 01 2022 01 23 Objective: Surgical site infections (SSIs) owing to nontuberculous Mycobacteria (NTM) have emerged as an important cause of hospital-acquired SSI leading to great morbidity and mortality. Among NTM, Mycobacterium abscessus is reported in these sites. Epidemiology and transmission of M. abscessus in humans is noticing crux changes. Case report: We hereby describe a case of SSI after lower segment cesarean section (LSCS), presenting as a skin and soft tissue infection (SSTI) owing to a NTM. Conclusion: Clinicians should be aware of the possibility of infections caused by M. abscessus in patients who develop SSIs, particularly if they do not respond to conventional first-line antimicrobial therapy. https://jfrh.tums.ac.ir/index.php/jfrh/article/view/1927