Tehran University of Medical Sciences Journal of Family and Reproductive Health 1735-8949 15 1 2021 04 25 53 60 EN Mahmoud Hajipour Research Center Office, Epidemiology Department, School of Public Health, Shahid Beheshti University of Medical Sciences, Tehran, Iran Maryam Soltani Razi Clinical Research Development Unit (RCRDU), Birjand University of Medical Sciences (BUMS), Birjand, Iran Roya Safari-Faramani Research Center for Environmental Determinants of Health, Health Institute, School of Health, Kermanshah University of Medical Sciences, Kermanshah, Iran Salman Khazaei Research Center for Health Sciences, Hamadan University of Medical Sciences, Hamadan, Iran Koorosh Etemad Department of Epidemiology, Environmental and Occupational Hazards Control Research Center, Faculty of Public Health, Shahid Beheshti University of Medical Sciences, Tehran, Iran Sharmin Rahmani Student Research Committee, Research Center for Environmental Determinants of Health, School of Health, Kermanshah University of Medical Sciences, Kermanshah, Iran Tannaz Valadbeigi Clinical Research Development Unit, Imam Hossein Hospital, Shahroud University of Medical Sciences, Shahroud, Iran Halime Yaghoobi Social Determinants in Health Promotion Research Center, Hormozgan University of Medical Sciences, Bandar Abbas, Iran Shahab Rezaeian Infectious Diseases Research Center, Kermanshah University of Medical Sciences, Kermanshah, Iran AND Clinical Research Development Center, Imam Reza Hospital, Kermanshah University of Medical Sciences, Kermanshah, Iran 2020 11 04 2021 01 24 Objective: Sleep disturbance during pregnancy is one of the most common maternal complaints. Not only does it play a crucial role in a mother’s life, but also it comes with a multitude number of complications. This study aimed at assessing the association between sleep disturbance in pregnancy and maternal and child outcomes. Materials and methods: This was a multicenter cross-sectional study, conducted on pregnant women across 11 provinces in Iran in 2018. Sleep disturbance as a composite variable was defined using the principal component analysis based on five questions. Abortion, anemia in the first and third trimester, gestational diabetes, gestational age, glucose tolerance test (GTT), fasting blood sugar (FBS), mode of delivery, low birth weight and stillbirth were defined as study outcomes. Results: Totally, 3675 pregnant women enrolled in the study. Most of the participants (84.5%) reported that their sleep duration is less than 8 hours per day. The prevalence of sleep disturbance was 20.7% (95% CI: 19.1, 22.3). After adjusting for maternal age, education, job, place of residency and physical violence, sleep disturbance would increase the odds of abortion (p=0.009), anemia in both first(p=0.001) and third (p=0.003) trimester, gestational age (p=0.049), abnormal FBS (p=0.015) and cesarean section (p<0.001). Conclusion: Regarding the effect of sleep quality on maternal outcomes, planning and implementing a suitable intervention in the context of primary health care is necessary. Increasing the awareness of mothers, health workers and medical personnel about the suitable quality and quantity of sleep during pregnancy is of great importance. https://jfrh.tums.ac.ir/index.php/jfrh/article/view/1597 https://jfrh.tums.ac.ir/index.php/jfrh/article/download/1597/555