Tehran University of Medical Sciences Journal of Family and Reproductive Health 1735-8949 6 2 2012 06 15 73 78 Shila Doaee Health Technology Assessment office, Deputy of curative affairs, MOHME, Tehran, Iran Alireza Oliyaeemanesh National Institute for Health Research, Health Technology Assessment, Standardization and Tariff Management, Deputy of curative affairs, MOHME, Tehran, Iran Mina Nejati Health Technology Assessment office, Deputy of curative affairs, MOHME, Tehran, Iran Mohamadreza Mobinizadeh Health Technology Assessment office, Deputy of curative affairs, MOHME, Tehran, Iran Parisa Aboee Health Technology Assessment office, Deputy of curative affairs, MOHME, Tehran, Iran Seyed Hasan Razavi Brain and Spinal Injury Repair Research Center, Tehran University of Medical Sciences, Tehran, Iran 2015 10 04 Objective: Health Technology Assessment (HTA) aims at informing healthcare policymakers, managers and practitioners of the "clinical consequences, but also the economic, ethical, and other social implications of the diffusion and use of a specific procedure or technique on medical practice". So considering the policy-oriented nature of HTA that calls for a close integration into the functioning and governance of health systems the present study focuses on executive processes and function of the HTA office of Iran. Materials and methods: Data of this review study were collected through documented sources and observations from 2007 to 2010. Results: Health Technology Assessment began its activities as a secretariat in the Deputy of Health in 2007 and it continues as a Health Technology Assessment Office at the Management of Health Technology Assessment, Standardization, and Tariff at the Deputy of curative affairs of MOHME in the beginning of 2010.14 Technology of modern medical equipment and 8 pharmaceutical medicine are assessed, Now many of measures for HTA establishment  such as cooperation National Institute of Health Research (NIHR), Holding scientific committee meetings, Establishing  the  Master's degree of  health technology assessment ,Building capacities for health technology assessment through education in major universities of the country. Conclusion: pay attention to health technology assessment, selection and application of proper technologies in the frameworks of policy-making and managerial strategies and make efforts to develop it with the support of the governmental in Iran is necessary. https://jfrh.tums.ac.ir/index.php/jfrh/article/view/146 https://jfrh.tums.ac.ir/index.php/jfrh/article/download/146/146