A Randomized Controlled Clinical Trial of Olive Oil Added to Human Breast Milk for Weight Gaining in Very Low Birth Weight Infants

Tehran University of Medical Sciences Journal of Family and Reproductive Health 1735-8949 5 3 2011 09 15 A Randomized Controlled Clinical Trial of Olive Oil Added to Human Breast Milk for Weight Gaining in Very Low Birth Weight Infants 73 78 Elaheh Amini Breast feeding Research Center, Tehran University of Medical Science, Tehran, Iran AND Fetal & Neonatal Research Center, Tehran, Iran Mamak Shariat Breast feeding Research Center, Tehran University of Medical Science, Tehran, Iran AND Fetal & Neonatal Research Center, Tehran, Iran Fatemeh Nayeri Breast feeding Research Center, Tehran University of Medical Science, Tehran, Iran AND Fetal & Neonatal Research Center, Tehran, Iran Firoozeh Nili Breast feeding Research Center, Tehran University of Medical Science, Tehran, Iran AND Fetal & Neonatal Research Center, Tehran, Iran Bita Ebrahim Breast feeding Research Center, Tehran University of Medical Science, Tehran, Iran Hosein Dalili Breast feeding Research Center, Tehran University of Medical Science, Tehran, Iran 2015 10 04 Objective: Evaluating the effect of vegetable oil, as a supplement to breast milk in increase the weight gaining of VLBW neonates. Materials and methods: In this single blind; Randomized clinical trials , in NICU of Vali-asr Hospital, Tehran University of Medical Sciences, 2005-2006;A total of 48 VLBW neonates referred & admitted to NICU, who did not have any major GI (especially NEC), respiratory or cardiac diseases; participated randomly in two groups: intervention & control.Vegetable oil was added to the milk of 25 neonates (0.5 cc per 30cc of milk) and the other 25neonates with similar conditions that were selected as a control group, did not get any type of supplementary nutrition. Daily feeding volume in both groups was 150-200 cc for each kilogram of body weight. Results: Weight gaining in interventional groups was considerably more than control group. (p<0.04).There were also significant statistical differences in hospitalization period between the two groups, 28.9 days in interventional and 20.33 days in control group, (p<0.03).However, no significant side effects were observed. Conclusions: There is no report regarding contraindication linking the use of vegetable oil intended for appropriate weight gaining or reducing hospitalization period to neonatal chronic diseases. https://jfrh.tums.ac.ir/index.php/jfrh/article/view/125 https://jfrh.tums.ac.ir/index.php/jfrh/article/download/125/125